Disease Information for Procarbazine (Matulane) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Athetosis
Choreoathetoid movement
Nightmares/excess dreaming (Paroniria)
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Macrocytosis/smear (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Dreaming/nightmares (Paroniria)
Drug induced Lung disease.
Drug induced Peripheral neuropathy.
Drug induced Pleural effusion
Pericardial effusion
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Antidepressant medication (examples)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Cytotoxic/chemotherapy medication (example)
DRUG/Impaired DNA metabolism effect/drug (example)
DRUG/Monoamine oxidase inhibitor activity present
DRUG/Monoamine oxidase inhibitor medication (example)
DRUG/Psychoactive/sedative drug (category)
Pathophysiology
Pathophysiology/Chronic intrinsic restrictive lung
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Benzamide N (1 methylethyl) 4 ((2 methylhydrazino)methyl), Benzethyzin, Ibenzmethyzin, MIH, N (1 methylethyl) 4 ((2 methylhydrazino)methyl)benzamide, N 4 isopropylcarbamoylbenzyl N' methylhydrazine, N isopropyl alpha (2 methylhydrazino) p toluamide, N Methylhydrazine, p (N' methylhydrazinomethyl) N isopropylbenzamide, PCB, PCZ, Procarbazin, procarbazine, Procarbazine (product), Procarbazine (substance), PROCARBAZINE PREPARATION, Procarbazine Sigma Tau Brand, Sigma Tau Brand of Procarbazine, Brand name/Matulane (Procarbazine)
Definition

Monoamine oxidase inhibitor antidepressant drug; oral preparation; used by specialist usually; major danger of hypertensive crisis with certain foods and drug interaction

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External Links Related to Procarbazine (Matulane) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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