Disease Information for Pinta

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Clinical Manifestations
Signs & Symptoms
Depigmented patches, skin
Hypopigmentation
Patchy pigmentation/face/neck/hands
Rash on legs/ankles
Disease Progression
Course/Acute
Course/Acute only
Demographics & Risk Factors
Sex & Age Groups
Population/Adult ('twenties')
Laboratory Tests
Microbiology & Serology Findings
Serum specific antibodies increased
Microlab/Lyme disease (ELISA/IFA) titer
Microlab/Treponema/Carateum isolation
Abnormal Lab Findings - Increased
FTA-ABS/Treponema pallidum (Lab)
Serologic syphilis test/STS/VDRL/Hinton (Lab)
Diagnostic Test Results
Pathology
PATH/Granulomatous tissue/specimen
Associated Diseases & Rule outs
Associated Disease & Complications
Pinta
Vitiligo
Disease Mechanism & Classification
Specific Agent
AGENT/Spirochete (ex)
AGENT/Spirochete/Borrelia/Treponema (category)
Pathophysiology
Pathophysiology/Granulomatous Infection
Process
PROCESS/Infection/agent specific (category)
PROCESS/Inflammatory/Granulomatous disease (ex)
PROCESS/Granulomatous Disease
Synonyms
Synonym
Azul, CARATE, E 133 PINTA, Infection by Treponema carateum, Mal del pinto, Pinta, Pinta (carate), Pinta (disorder), Pinta unspecified, Pinta unspecified (disorder), Treponema carateum infection, Synonym/Carate
Treatment
Drug Therapy - Indication
RX/Antibiotic
RX/Penicillin
Definition

An infectious disease of the skin caused by Treponema carateum that occurs only in the western hemisphere; Age of onset is between 10 and 20 years of age; This condition is characterized by marked changes in the skin color and is believed to be transmitted by direct person-to-person contact;----------- Pinta is an endemic treponematosis caused by Treponema carateum; It is an ancient disease that was first described in the 16th century in Aztec and Carib Amerindians; In 1938, treponemes indistinguishable from those causing yaws and syphilis were demonstrated in lesions of a Cuban patient; Pinta is characterized by chronic skin lesions that occur primarily in young adults; Pathophysiology: Like other treponematoses, pinta is classified into an early and late stage; The early stage comprises the initial lesion and the secondary lesions, while the late stage comprises the latent phase and tertiary stage; After an incubation period of approximately 2-3 weeks, the initial lesion appears on the skin; The primary lesion is a papule or erythematosquamous plaque usually found on exposed surfaces of the legs, dorsum of the foot, forearm, or hands; The lesion slowly enlarges and becomes pigmented and hyperkeratotic; It is often accompanied by regional lymphadenopathy; Disseminated lesions, referred to as pintids, are similar to the primary lesion and may appear 3-9 months after infection; These secondary lesions vary in size and location and become pigmented with age; Late or tertiary pinta is characterized by disfiguring pigmentary changes, hypochromia, achromic lesions, and hyperpigmented and atrophic lesions; The pigmentary changes often produce a mottled appearance of the skin: Lesions may appear red, white, blue, violet, and brown; In the US: Pinta does not occur in the United States; Internationally: Pinta exists in scattered foci in rural areas in Central and South America;

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External Links Related to Pinta
Google
Wikipedia
Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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