Disease Information for Phenobarbital (Luminal) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Athetosis
Behavior problems
Choreoathetoid movement
Hyperkinesia
Nystagmus
Tics/sign
Depressed/discouraged/sad
True Vertigo Sign Confirmed
Laboratory Tests
Abnormal Lab Findings - Decreased
Folic acid/Folate (Lab)
Phosphate Serum (Lab)
PT -Prothrombin time (Lab)
Abnormal Lab Findings - Increased
PCO2, arterial blood (Lab)
Testosterone Total (Lab)
Diagnostic Test Results
Isotope Scan
Isotope/RAI uptake/quantitative high thyroid (I 123)
Associated Diseases & Rule outs
Associated Disease & Complications
DRESS/Drug Hypersensitivity Syndrome
Drug induced Balance/Ataxia poblems
Drug Induced Choreoathetosis
Fixed cutaneous eruption
Hypophosphatemia
Neurobehavior Problems
Porphyria, attack, acute intermittant
Stevens-Johnson syndrome
Disease Mechanism & Classification
Drugs
DRUG/Anticonvulsant/antiepilepsy medication (example)
DRUG/Important Acute care drugs (example)
DRUG/Narrow range of safety (effect/toxic)
DRUG/Oral contraceptive effect weakened
DRUG/Psychoactive/sedative drug (category)
DRUG/Sedative/hypnotic medication (example)
DRUG/Tranquilizers/Anxiolytics (ex)
DRUG-Liver metabolism/bile excretion
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
2 4 6(1H 3H 5H) Pyrimidinetrione 5 ethyl 5 phenyl, 5 Ethyl 5 phenyl 2 4 6(1H 3H 5H) pyrimidinetrione, Acid Phenylethylbarbituric, Phenemal, PHENO, Phenobarbital, Phenobarbital (product), Phenobarbital (substance), PHENOBARBITAL PREPARATION, Phenobarbital product, Phenobarbitone, Phenobarbitone chemical, Phenobarbitone chemical (substance), Phenobarbitone product, Phenylbarbital, Phenylethylbarbituric Acid, Phenylethylmalonylurea, Brand name/Donnatal (Phenopbarbital-Atropine-homatropine), Brand name/Luminal (Phenobarbital), Britain-BNF/Phenobarbitone (Phenobarbital)
Treatment
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 100 mgm (Unit/Pill/Capsule size)
DRUG/Dose 15 mgm (Unit/Pill/Capsule size)
DRUG/Dose 16 mgms (Unit/Pill/Capsule size)
DRUG/Dose 30 mgm (Unit/Pill/Capsule size)
DRUG/Dose 32 mgm (Unit/Pill/Capsule size)
DRUG/Dose 60 mgm (Unit/Pill/Capsule size)
DRUG/Dose 65 mgms (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Dose guided by blood levels
DRUG/Dose liquid/syrup/suspension form
DRUG/Dose TID Medication
DRUG/Generic available
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Oral medication (ex)
Other Treatments
TX/Hemodialysis.
Definition

Long acting Barbiturate sedative hypnotic drug; oral and parenteral preparation;used as anticonvulsant; narrow safety range with respiratory depression/arrest on overdose especially with alcohol abuse

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External Links Related to Phenobarbital (Luminal) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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