Disease Information for Penicillin/extreme doses/toxicity

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Clinical Manifestations
Signs & Symptoms
Confusion/Disoriented
Headache
Headache, frontal
Myoclonus/Myoclonic jerks on exam
Seizures
Stupor/poor reponse to stimulus
Agitation
Diagnostic Test Results
CT Scan
CT Scan/Head Brain Swelling/Edema
MRI/Head Brain Swelling/Edema
Associated Diseases & Rule outs
Associated Disease & Complications
Acute Renal Failure
Anemia
Azotemia/Acute
Cerebral edema
Convulsions (grand mal)
Drug induced Anemia.
Drug induced Renal failure,
Drug induced Seizures
Sedation/torpor induced
Toxic nephritis/Chronic persistent
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/antibacterial drug (example)
DRUG/Antifungal/systemic antibiotic (example)
DRUG/Penicillins (example)
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Definition

High doses of penicillin sometimes needed but always cause toxicity syndrome [cns] over 20 to 30 million units per day; seizures occur with csf pressure and often salt load from iv dose; seen more often in renal disease

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External Links Related to Penicillin/extreme doses/toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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