Disease Information for Pemphigus

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Beau's lines/Mees lines fingernails
Blisters
Bulla/bullous rash
Hair loss
Nail Striations
Nikolskys sign
Non-scarring Alopecia/balding
Rash/Lesions occur on pressure points/Acral lesions
Skin fragile/thin/easily torn
Skin sloughing/denuded/raw/oozing areas
Vesicobullous rash/lesions in Children
Vesicobullous rashes
Oral lesion/ulcer
Oral mucosa erythematous lesions
Oral Mucosal Erosive Lesions
Oral Mucosal Punctate Lesions
Oral/pharyngeal slough/blisters/mucositis
Vaginal/Vulva ulcers
Chills
Laboratory Tests
Microbiology & Serology Findings
Microlab/Tzanck test/Rounded acantholytic cells
Abnormal Lab Findings (Non Measured)
Anti-Desmocolin-1 test/blood (labs)
Abnormal Lab Findings - Decreased
Hematocrit (Lab)
Hemoglobin (Lab)
RBC/Red Blood Count (Lab)
Abnormal Lab Findings - Increased
Anti-epidermal antibody (Lab)
Eosinophiles (LAB)
Cryoglobulins (Lab)
Fibrinogen, plasma (Lab)
IGA Antigliadin antibodies
IGE/Immunoglobulin E (Lab)
Potassium, serum (Lab)
Diagnostic Test Results
Pathology
BX/Skin biopsy/Acantholysis epidermis
BX/Skin biopsy/Epidermal fluorescent antibody
Associated Diseases & Rule outs
Rule Outs
Erythema multiforme
Hand, foot and mouth disease
Pemphigoid, bullous
Smallpox
Stevens-Johnson syndrome
Associated Disease & Complications
Alopecia areata
Anemia
Eosinophilia Hypereosinophilia
Hyperkalemia
Disease Mechanism & Classification
Class
CLASS/Dermatologic/Subcutaneous (category)
Process
PROCESS/Reference organ/system (category)
Treatment
Drug Therapy - Indication
RX/Corticosteroid (Cortisone)
RX/Dexamethasone (Decadron)
Definition

Group of chronic blistering diseases characterized histologically by acantholysis and blister formation within the epidermis.

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External Links Related to Pemphigus
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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