Disease Information for Paraneoplastic syndrome

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Clinical Manifestations
Signs & Symptoms
Breast Swelling Bilateral
Erythroderma
Increased pigmentation/tanning/hyperpigmented
Buffalo hump
Moon-like facies
Fasting intolerant
Vomiting
Vomiting recurrent
Diffuse Aches and Pains
Symmetrical muscle involvement/stiffness
Symmetrical muscle/pain, weakness
Weak/Weak as a kitten (symptom)
Ataxia
Cerebellar movement disorder/signs
Clumsiness/poor coordination
Cognitive defect
Limb Ataxia
Staggering Gait
Weakness/Diffuse motor loss
Asthenia
Enervated/extreme acute fatigue
Total body pain/truncal/extremities
Weakness
Weakness non-neuromuscular/systemic
Clinical Presentation & Variations
Presentation/Progressive Motor Sensory Polyneuropathy
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Established Disease Population
Patient/Cancer
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Anti-Neuron [ANNA ] Paraneoplastic antigens (1,2,2a) abnormalities
Fasting hypoglycemia (Lab)
Paraneoplastic Antibody Panel (Lab)
Abnormal Lab Findings - Decreased
Glucose, blood (Lab)
Osmolality, serum (Lab)
Abnormal Lab Findings - Increased
Anti-GAD antibodies
Anti-Glutamic Acid decarboxylase antibodies/GAD
Anti-Hu/ANNA-IIA Paraneoplastic antigen (Lab)
Anti-Purkinje/APCA/Anti-yo titer (Lab)
Anti-Ta/Neuronal antibodies (Lab)
Anti-Yo antibodies
ACTH/Corticotrpin/Adrenocortical Hypertrophic hormone (Lab)
Calcium, serum (Lab)
Cortisol (Lab)
CSF Anti-Hu (ANNA 2a) antibodies
Associated Diseases & Rule outs
Rule Outs
Eaton-Lambert syndrome
Polymyalgia rheumatica
Associated Disease & Complications
Acanthosis nigricans
Acromegaly
Amyotrophic lateral sclerosis
Ataxic neuropathy
Carcinomatous cerebellar/motor syndrome
Carcinomatous neuropathic syndrome
Cerebral cortical atrophy
CNS disease/involvement
Dementia
Dermatitis, neutrophilic/Sweets
Eaton-Lambert syndrome
Feminization/male
Gynecomastia
Hypercalcemia
Hypercalcemia of Malignancy
Hyperpigmentation
Inflammatory myopathy
Metabolic encephalopathy
Motor neuropathy
Neuropathy
Paraneoplastic syndrome
Polychondritis
Stiff-man syndrome
Vomiting Excess/Chronic
Ataxia Disorder
Disease Mechanism & Classification
Class
CLASS/Endocrine gland (category)
Pathophysiology
Pathophysiology/Increased estrogen secretion
Process
PROCESS/Autoimmune disorder (ex)
PROCESS/Complicating disorder (ex)
PROCESS/Endocrine/humoral disorders (category)
PROCESS/Neoplastic (category)
PROCESS/Paraneoplastic disorder (ex)
PROCESS/Paraneoplastic neurologic disorder
PROCESS/Pathophysiologic disorder (category)
Definition

In patients with neoplastic diseases a wide variety of clinical pictures which are indirect and usually remote effects produced by tumor cell metabolites or other products.

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External Links Related to Paraneoplastic syndrome
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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