Disease Information for PANDAS/Tic Disorder

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Clinical Manifestations
Signs & Symptoms
Facial tic
Attacks, neurologic, recurrent, varied
Behavior problems
Extrapyramidal signs
Fine-motor coordination problems
Finger to nose test abnormality
Inattention
Intelligence normal
Involuntary movements
Neurologic manifestations/signs
Neurological symptoms/signs
Tics/sign
Vocal tic
Behavior characteristic/oppositional/rigid/stubborn
Chronic/recurrent anxiety
Compulsive behavior
Destructive Behavior
Idea Fixed/Singleness of thinking
Queer bizarre behavior/change
Ritualistic behavior patterns
Separation anxiety/Child
Stubborn
Sore throat/Pharyngitis
Sore Throat/Throat Pain
Throat Conditions
Disease Progression
Course/Paroxysmal
Course/Recurrent
Course/Self limited usually
Onset/Acute
Onset/Overnight
Demographics & Risk Factors
Established Disease Population
Patient/Phenothiazine treated
Patient/Humoral immune defect
Population Group
Population/Previously well
Sex & Age Groups
Population/Child
Population/Old child
Population/Pre-teen
Laboratory Tests
Microbiology & Serology Findings
Microlab/Throat culture positive
Microlab/Throat culture/beta strep culture/type A
Abnormal Lab Findings - Increased
Anti-Basal Ganglion Neuronal Antibody (Lab)
Anti-Streptolysin DNAase B (Lab)
ASOT/Anti-streptolysin-O titer (Lab)
Associated Diseases & Rule outs
Rule Outs
Chorea, Sydenham's
Gilles de Tourette syndrome
Associated Disease & Complications
Anxiety
Autoimmune disease
Extrapyramidal disease/manifestation
Habit spasm/tic
Neurobehavior Problems
Neurologic side effects
PANDAS/Tic Disorder
Disease Synergy - Causes
Synergy/Stress/Anxiety
Disease Mechanism & Classification
Class
CLASS/Basal ganglia lesion/involvement/disorders (ex)
CLASS/Cerebellar disorder (ex)
CLASS/Neurologic (category)
Pathophysiology
Pathophysiology/Humoral autoantibody
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Autoimmune disorder (ex)
PROCESS/Episodic disorder (ex)
PROCESS/Hierarchic item/group of diseases (category)
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Vegetative-Autonomic/Endocrine (category)
Synonyms
Synonym
9 15 TIC DISORDERS, AUTOIMMUNE DIS NERVOUS SYSTEM, AUTOIMMUNE DIS NEUROL, Autoimmune Disease Neurologic, Autoimmune Diseases Nervous System, Autoimmune Diseases Neurologic, Autoimmune Diseases of the Nervous System, Autoimmune Disorders Nervous System, Autoimmune Disorders of the Nervous System, AUTOIMMUNE NERVOUS SYSTEM DIS, Autoimmune Nervous System Diseases, autoimmune nervous system disorder, Disease Neurologic Autoimmune, Diseases Neurologic Autoimmune, Group A streptococcus, Micrococcus scarlatinae, NERVOUS SYSTEM AUTOIMMUNE DIS, Nervous System Autoimmune Diseases, NEUROL AUTOIMMUNE DIS, Neurologic Autoimmune Disease, Neurologic Autoimmune Diseases, S pyogenes, spasm tic, STREP GROUP A, STREP PYOGENES, Streptococc Lancefield group A, Streptococcus erysipelatos, streptococcus group A, Streptococcus hemolyticus, Streptococcus Lancefield group A, Streptococcus Lancefield group A (organism), Streptococcus pyogenes, Streptococcus pyogenes (organism), Streptococcus pyogenes Rosenbach 1884, Streptococcus scarlatinae, tic, Tic (dup) (finding), Tic (finding), TIC DIS, Tic disorder, Tic disorder (disorder), Tic disorder unspecified, Tic disorder unspecified (finding), Tic disorders, Tic disorders (finding), tic spasm, Tics, Synonym/Pediatric Autoimmune Neuropsychiatric Disorder Associated Streptococcus, Synonym/Post-streptococcal Autoimmune Neurologic Pediatric Immune Disorder
Treatment
Drug Therapy - Indication
RX/Antibiotic
RX/Gamma globulin (intravenous, high dose)
RX/Penicillin
RX/Valproic/divalproex (Depakote/Epival)
Other Treatments
TX/Plasmapheresis/exchange.
Definition
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External Links Related to PANDAS/Tic Disorder
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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