Disease Information for Pamidronate (Aredia) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Osteonecrosis of Jaw
Disease Mechanism & Classification
Drugs
DRUG/Bisphosphonate drug (example)
DRUG/Important Acute care drugs (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
admin, Pamidronate (Aredia), Brand name/Aredia (Pamidronate)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Injectable medication (parenteral)
DRUG/Injectable preparation only
DRUG/Intravenous administraton RX
DRUG/Intravenous only RX
Definition

Bisphosphonate drug inhibits osteoclast activity; used in Paget"s bone disease; used in hypercalcemia of malignancy and ostelytic metastatic bone lesions parenteral oral preparation.----------------------------------

Parenteral bisphosphonates are particularly useful for patients who cannot tolerate oral bisphosphonates.Pamidronate, 60–120 mg intravenously over 2–4 hours, may produce improvements lasting several months. Alkaline phosphatase may continue to drop for 6 months after treatment. (See Treatment of Hypercalcem

[currentdxrx 2005]

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External Links Related to Pamidronate (Aredia) Administration/Toxicity
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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