Disease Information for Ovarian failure, premature

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Clinical Manifestations
Signs & Symptoms
Plethora/Red face/Ruddy look
Breast atrophy
Blotchy rash/variable
Facial erythema
Facial flushing/Beet red
Flushing
Hot Flushes
Increased wrinkling/skin
Abdominal Distension
Abdominal distension/protrusion/sign
Abdominal Distention
Amenorrhea
Amenorrhea, primary
Amenorrhea, secondary
Cervix/small atrophic
Decreased Vaginal Lubrication
Hot flashes
Painful coitus or dyspareunia
Uterine Bleeding
Uterus and adnexa/small/Pelvic exam
Vaginal Bleeding
Vaginal dryness
Weight gain
Demographics & Risk Factors
Established Disease Population
Patient/Atrophic vagina/vaginitis
Patient/Autoimmune polyglandular disease
Population Group
Woman
Sex & Age Groups
Population/Adult Aged Only
Population/Adult/all
Population/Female
Population/Woman patient
Laboratory Tests
Abnormal Lab Findings - Decreased
Estradiol Serum (Lab)
Thyroid Binding Globulin (Lab)
URINE Pregnanediol (Lab)
URINE/Estradiol (Lab)
Abnormal Lab Findings - Increased
FSH/Follicle Stmulating Hormone/ICSH (Lab)
LH/Leutinizing Hormone (Lab)
URINE FSH
URINE Leutininzing hormone
Diagnostic Test Results
Pathology
BX/Ovary abnormal
PATH/Vaginal smear/parabasal cells predominate
CT Scan
CT Scan/Bone densometry/density decreased
CT/Dexa-Scan Bone density Abnormal
Associated Diseases & Rule outs
Associated Disease & Complications
Atrophic vaginitis
Dyspareunia
Early menopause
Infertility/sterility, female
Male osteoporosis syndrome
Menopause
Menopause/ovary disorder/seconday
Osteoporosis/osteopenia
Ovarian Dysfunction
Ovarian failure, premature
Ovarian hypofunction
Pathologic fractures
Metabolic Bone Disease
Disease Mechanism & Classification
Class
CLASS/Ovary disorder (ex)
CLASS/Ovary/uterus/female genital (category)
Pathophysiology
Pathophysiology/Gene locus 2p21-p16
Pathophysiology/Gene locus Chromosome 2
Pathophysiology/Gene locus Chromosome X.
Pathophysiology/Gene Locus Identified/OMIM database
Pathophysiology/Gene locus Xp21.3
Pathophysiology/Gene locus Xp22.1
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Ovarian dysfunction anovulation
Pathophysiology/Osteoporosis Secondary
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Autoimmune disorder (ex)
PROCESS/Complicating disorder (ex)
Treatment
Drug Therapy - Indication
RX/Oral contraceptive
Definition

Premature failure of ovulation associated with hypergonadotropinism and hypoestrogenism in women under the age of 40. The etiology appears to be multifactorial and many cases are idiopathic. When follicles are present but the ovaries are unable to respond to gonadotropins, resistant ovary syndrome results and this may be associated with autoimmune disease. Even when there is a loss of ovarian follicles, it is not always complete. Permanent and irreversible loss of follicles is termed premature menopause (MENOPAUSE, PREMATURE).

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External Links Related to Ovarian failure, premature
Google
Wikipedia
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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