Disease Information for Osteopetrosis (Albers-Schonberg)

Marble bone disease; Excessive formation of dense trabecular bone leading to pathological fractures, OSTEITIS, SPLENOMEGALY with infarct, ANEMIA, and extramedullary hemopoiesis -------------------------- Osteopetrosis; Albers-Schonberg Disease; Marble Bones

Osteosclerosis Fragilis Generalisata; Osteopetrosis, autosomal dominant; adult type; Osteopetrosis, autosomal recessive; malignant infantile type ; Osteopetrosis, mild autosomal recessive; intermediate type; Osteopetrosis may be inherited as either a dominant or recessive trait and is marked by increased bone density, brittle bones, and, in some cases, skeletal abnormalities; Although symptoms may not initially be apparent in people with mild forms of this disorder, trivial injuries may cause bone fractures due to abnormalities of the bone;There are three major types of osteopetrosis: the malignant infantile form, the intermediate form, and the adult form; The adult form is milder than the other forms, and may not be diagnosed until adolescence or adulthood when symptoms first appear; The intermediate form, found in children younger than ten years old, is more severe than the adult form but less severe than the malignant infantile form; The malignant infantile form is apparent from birth and frequently shortens life expectancy; It is not related to cancer, despite the name --------------[NORD]-----------------------------

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