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Disease Information for Osteitis fibrosa cystica

Clinical Manifestations

Signs & Symptoms

Diffuse Aches and Pains

Total body pain/truncal/extremities

Typical Clinical Presentation

Presentation/Fractures Pathologic Minimal Trauma

Demographics & Risk Factors

Established Disease Population

Patient/Hyperparathyroidism

Patient/Uremia/Chronic renal disease

Laboratory Tests

Abnormal Lab Findings - Increased

Alkaline phosphatase, serum (Lab)

Diagnostic Test Results

Pathology

PATH/Parathyroid Hyperplasia

BX/Bone biopsy/abnormal

X-RAY

Xray/Chest abnormal

Xray/Calcifications apparent/Chest

Xray/Chest/Lung fields/Abnormal

Xray/Posterior calcified mass on rib/Chest

Xray/Bone abnormality

Xray/Bone lesion, solitary lytic

Xray/Metadiaphysis lesion/Site usual Present

Associated Diseases & Rule outs

Rule Outs

Paget's disease (osteitis deformans)

Associated Disease & Complications

Bone Marrow Fibrosis

Craniofacial osteogenic sarcoma

Osteitis fibrosa cystica

Osteoporosis/osteopenia

Platybasia

Mass in Bone

Disease Mechanism & Classification

Class

CLASS/Bone disorder (ex)

CLASS/Diffuse bone involvement/disorder (ex)

CLASS/Skeletal (category)

Pathophysiology

Pathophysiology/Skeletal defomities/acquired

Process

PROCESS/Complicating disorder (ex)

PROCESS/Complication/primary failed organ/system (ex)

PROCESS/Reference organ/system (category)

PROCESS/Structural/anatomic/foreign body (category)

Synonyms

Synonym

Big head, bone disease Recklinghausen, Bran disease, Brown tumor, Brown tumour, disease Von Recklinghausen bone, ENGEL RECKLINGHAUSEN SYNDROME, Fibro osteoclasia, fibrosa osteitis cystica (generalisata), Fibrous osteodystrophy, Hyperparathyroid bone disease, OSTEITIS FIBROSA CYSTICA, osteitis fibrosa cystica (generalisata), OSTEITIS FIBROSA CYSTICA GENERALISATA, Osteitis fibrosa cystica generalisata (disorder), OSTEITIS PARATHYROID, Osteodystrophia fibrosa, Recklinghausen bone disease, RECKLINGHAUSEN DIS OF BONE, Recklinghausen Disease Bone, Recklinghausen Disease of Bone, RECKLINGHAUSEN DISEASE OF BONES, RECKLINGHAUSENS DIS OF BONE, Recklinghausens Disease Bone, Recklinghausen's Disease of Bone, Von Recklinghausen disease bone, von Recklinghausen's bone dis, Von Recklinghausen's bone disease, Von Recklinghausen's Disease of Bone, Synonym/Brown tumor/parathyroidism

Definition

A fibrous degeneration, cyst formation, and the presence of fibrous nodules in bone, usually due to HYPERPARATHYROIDISM.

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External Links Related to Osteitis fibrosa cystica

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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