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Disease Information for Octreotide (Sandostatin) Administration/Toxicity

Associated Diseases & Rule outs

Associated Disease & Complications

Cholelithiasis

Drug induced Cholelithiasis

Steatorrhea

Disease Mechanism & Classification

Drugs

DRUG/Antidote/specific medication (example)

DRUG/Chemotherapeutics/cancer drugs/etc (category)

DRUG/Hormonal agents/cancer chemotherapy (example)

DRUG/Important Acute care drugs (example)

DRUG/Somatostatin analog/drug

DRUG/Specialized usage (example)

DRUG/Suppresses TSH,Insulin-release,cholecytokinin,prolactin

Pathophysiology

Pathophysiology/Antiserotonin/VIP/secretin/gastrin effect

Pathophysiology/Anti-splanchnic intestinal hormone/effect

Pathophysiology/Anti-STH/Glucagon/Insulin effect

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

1 2 Dithia 5 8 11 14 17 pentaazacycloeicosane Cyclic Peptide Deriv, D Phenylalanyl L cysteinyl L phenyl alanyl D tryptophyl L lysyl L threonyl N (2 hydroxy 1 (hydroxymethyl)propyl) L cysteinamide Cyclic (2 )7) Disulfide, D Phenylalanyl L cysteinyl L phenylalanyl D tryptophyl L lysyl L threonyl L cysteinyl L threoninol Cyclic (2 )7) Disulfide, D Phenylalanyl L cysteinyl L phenylalanyl D tryptophyl L lysyl L threonyl N ((1R 2R) 2 hydroxy 1 (hyroxymethyl)propyl) L cysteinamide Cyclic (2 )7) disulfide, L Cysteinamide D phenylalanyl L cysteinyl L phenylalanyl D tryptophyl L lysyl L threonyl N (2 hydroxy 1 (hydroxymethyl)propyl) cyclic (2 7) disulfide (R (R* R*)), Octreotide, Octreotide (substance), OCTREOTIDE PREPARATION, Octreotide preparation (product), Octreotide preparation (substance), Brand name/Sandostatin (Octreotide)

Treatment

Drug Dosage

DRUG/.$$$$$ Most Expensive

DRUG/Dose Bolus method/infusion rate (CONFIRM this)

DRUG/Dose Depot injection option

DRUG/Dose special schedule/course

DRUG/Dose Unit dose Vial preparation

DRUG/Half life Serum 1.7 hrs

DRUG/Half-life relatively short

DRUG/Infusion option medication

DRUG/Injectable medication (parenteral)

DRUG/Injectable preparation only

DRUG/Intramuscular injection RX

DRUG/Intravenous administraton RX

DRUG/Subcutaneous administration medication

-Pharmacology Drug Renal clearance predominant

Definition

Synthetic somatostatin drug: used in cancer chemotherapy as hormonal agent biologic activity modifier; often for symptom relief; indications include cancinoid syndrome and overdose of sulfonoureas/hypoglycemic drugs

(Edit)

External Links Related to Octreotide (Sandostatin) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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