Disease Information for Octreotide (Sandostatin) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Cholelithiasis
Drug induced Cholelithiasis
Steatorrhea
Disease Mechanism & Classification
Drugs
DRUG/Antidote/specific medication (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Hormonal agents/cancer chemotherapy (example)
DRUG/Important Acute care drugs (example)
DRUG/Somatostatin analog/drug
DRUG/Specialized usage (example)
DRUG/Suppresses TSH,Insulin-release,cholecytokinin,prolactin
Pathophysiology
Pathophysiology/Antiserotonin/VIP/secretin/gastrin effect
Pathophysiology/Anti-splanchnic intestinal hormone/effect
Pathophysiology/Anti-STH/Glucagon/Insulin effect
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1 2 Dithia 5 8 11 14 17 pentaazacycloeicosane Cyclic Peptide Deriv, D Phenylalanyl L cysteinyl L phenyl alanyl D tryptophyl L lysyl L threonyl N (2 hydroxy 1 (hydroxymethyl)propyl) L cysteinamide Cyclic (2 )7) Disulfide, D Phenylalanyl L cysteinyl L phenylalanyl D tryptophyl L lysyl L threonyl L cysteinyl L threoninol Cyclic (2 )7) Disulfide, D Phenylalanyl L cysteinyl L phenylalanyl D tryptophyl L lysyl L threonyl N ((1R 2R) 2 hydroxy 1 (hyroxymethyl)propyl) L cysteinamide Cyclic (2 )7) disulfide, L Cysteinamide D phenylalanyl L cysteinyl L phenylalanyl D tryptophyl L lysyl L threonyl N (2 hydroxy 1 (hydroxymethyl)propyl) cyclic (2 7) disulfide (R (R* R*)), Octreotide, Octreotide (substance), OCTREOTIDE PREPARATION, Octreotide preparation (product), Octreotide preparation (substance), Brand name/Sandostatin (Octreotide)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Dose Bolus method/infusion rate (CONFIRM this)
DRUG/Dose Depot injection option
DRUG/Dose special schedule/course
DRUG/Dose Unit dose Vial preparation
DRUG/Half life Serum 1.7 hrs
DRUG/Half-life relatively short
DRUG/Infusion option medication
DRUG/Injectable medication (parenteral)
DRUG/Injectable preparation only
DRUG/Intramuscular injection RX
DRUG/Intravenous administraton RX
DRUG/Subcutaneous administration medication
-Pharmacology Drug Renal clearance predominant
Definition

Synthetic somatostatin drug: used in cancer chemotherapy as hormonal agent biologic activity modifier; often for symptom relief; indications include cancinoid syndrome and overdose of sulfonoureas/hypoglycemic drugs

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External Links Related to Octreotide (Sandostatin) Administration/Toxicity
Google
Wikipedia
Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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