Disease Information for Nocturnal myoclonus syndrome

Clinical Manifestations
Signs & Symptoms
Cramping in Extremities
Abnormal movements/involuntary
Cognitive defect
Daytime Sleepiness
Myoclonus/Myoclonic jerks on exam
Nocturnal body movements/legs moving
Nocturnal Myoclonus
Sleep attacks/extreme daytime drowsiness
Sleep disturbance
AM/exhaustion,non-refreshing sleep
Nocturnal awakenings Events Phenomenon
Disease Progression
Course/Periodic Episodic
Demographics & Risk Factors
Established Disease Population
Patient/Sleeping status
Diagnostic Test Results
Other Tests & Procedures
Test/Sleep Study Abnormal
TEST/Sleep latency short/sleep study
Associated Diseases & Rule outs
Rule Outs
Convulsions (grand mal)
Associated Disease & Complications
Nocturnal myoclonus syndrome
Sleep Fragmentation
Disease Synergy - Causes
Synergy/Sleep deprivation
Disease Mechanism & Classification
CLASS/Neurologic (category)
Pathophysiology/Dysomnia/hypersomnias (ex)
Pathophysiology/Short REM latency
PROCESS/Vegetative-Autonomic/Endocrine (category)
Drug Therapy - Indication

Excessive periodic leg movements during sleep that cause micro-arousals and interfere with the maintenance of sleep; This condition induces a state of relative sleep deprivation which manifests as excessive daytime hypersomnolence; The movements are characterized by repetitive contractions of the tibialis anterior muscle, extension of the toe, and intermittent flexion of the hip, knee and ankle; (Adams et al, Principles of Neurology, 6th ed, p387)-------------------------------------------------.

Myoclonus, General; Subdivisions:Action Myoclonus; Arrhythmic Myoclonus; Dyssynergia Cerebellaris Myoclonica; Familial Arrhythmic Myoclonus; Hereditary Essential Myoclonus; Infantile Myoclonic Encephalopathy and Polymyoclonia; Intention Myoclonus; Nocturnal Myoclonus; Opsoclonus; Palatal Myoclonus; Paramyoclonus Multiple; Pathological Myoclonus; Postanoxic Intention Myoclonus; Postencephalitic Intention Myoclonus; Progressive Myoclonic Epilepsy; Respiratory Myoclonus; Rhythmical Myoclonus; Segmental Myoclonus; Stimulus-Sensitive Myoclonus; Myoclonus is a neurological movement disorder characterized by sudden, involuntary contractions of skeletal muscles; Based on the various symptoms, there are three types of Myoclonus: Intention Myoclonus, Rhythmical Myoclonus, and Arrhythmic Myoclonus;

Intention Myoclonus (Action Myoclonus) includes Postanoxic Myoclonus and Postencephalitic Myoclonus; Arrhythmic Myoclonus (stimulus-sensitive myoclonus) includes: Hereditary Essential Myoclonus (paramyoclonus multiplex), Hyperexplexia (Essential Startle Disease), Opsoclonus (Infantile Myoclonic Encephalopathy, Polymyoclonia Familial Arrhythmic Myoclonus), Progressive Myoclonic Epilepsy, Ramsay Hunt Syndrome (Dyssynergia Cerebellaris Myoclonia);

Rhythmical Myoclonus includes (Segmental Myoclonus), Nocturnal Myoclonus, Palatal Myoclonus, and Respiratory Myoclonus; [NORD]


External Links Related to Nocturnal myoclonus syndrome
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)