Disease Information for Nitrous oxide (N2O) Administration/Toxicity/abuse

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Clinical Manifestations
Signs & Symptoms
Arrhythmia signs/irregular pulse
Irregular rhythm/heartbeat
Acute ataxia
Ataxia/Posterior columns
Confusion/Disoriented
Headache
Headache, frontal
Intoxicated state/ataxia/slurred speech
Sensory Ataxia
Slurred speech
Slurred Speech/Acute
Staggering Gait
Trance like State/Intoxication
Unable to tandem walk/straight line
Unconscious/Narcosis status
Euphoria/Elated/'high' behavior/Gaiety
Hallucination/visual
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Macrocytosis/smear (Lab)
Diagnostic Test Results
CT Scan
CT Scan/Head Brain Swelling/Edema
MRI/Head Brain Swelling/Edema
Associated Diseases & Rule outs
Rule Outs
Pernicious anemia
Tabes dorsalis
Associated Disease & Complications
Cardiac arrhythmias
Cerebral edema
Coma/Unconscious
Drug induced Anemia.
Drug induced Folate/B12 interference
Hallucinations
Megaloblastic anemia/disease
Paraplegia, spastic
Peripheral neuropathy
Polyneuritis
Posterior column disease/cord
Toxic peripheral/polyneuropathy
Ataxia Disorder
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Anesthetic inhalant agent (example)
DRUG/Gases/anesthetics/inhalants meds (category)
Pathophysiology
Pathophysiology/Inhibited methionine synthetase
Pathophysiology/Oxidizes methyl B12/cellular inactivates
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/NOT Diagnosed on USUALToxic screens
TOXIN/Onset Immediate/Minutes
TOXIN/Street drug/inhalant snuffing (ex)
Definition

recreational use can lead to b12 deficiency and ataxia neuropathic syndromes

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External Links Related to Nitrous oxide (N2O) Administration/Toxicity/abuse
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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