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Disease Information for Nitroglycerin (Nitrostat) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Dizzy on Standing/Giddy Response

Orthostatic drop in blood pressure

Postural Hypotension Non-neural

Pulse pressure/wide

Red/erythema skin discoloration

Tachycardia/Fast heart rate

Erythroderma

Headache

Collapse/Prostration

Laboratory Tests

Abnormal Lab Findings - Increased

Methemoglobin (Lab)

URINE Methemoglobin

Associated Diseases & Rule outs

Associated Disease & Complications

Cluster/migraine headache syndrome

Methemoglobinemia

Orthostatic syncope Hypotension

Syncope/Fainting

Vascular headache

Disease Synergy - Causes

Synergy/Migraine trigger/attack

Synergy/Trinitrotoluene toxicity

Disease Mechanism & Classification

Drugs

DRUG/Anti-anginal medication (example)

DRUG/Cardiovascular meds (examples)

DRUG/Direct arteriolar vasodilator (example)

DRUG/Drug tolerance/effect

DRUG/Important Acute care drugs (example)

DRUG/Injectable antihypertensive med (example)

DRUG/Nitrate/Nitroglycerin medication (example)

DRUG/Preload reduction effect

DRUG/Tachyphylaxis occurs

Pathophysiology/Afterload reduction/effect

DRUG/Unction/ointment/gel dermatologic application

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

1 2 3 propanetriol trinitrate, Glyceryl trinitr (generic add), glyceryl trinitrate, Glyceryl trinitrate (generic additions), Glyceryl trinitrate (generic additions) (product), Glyceryl trinitrate (generic additions) (substance), Glyceryl trinitrate (product), Glyceryl trinitrate product, GTN Glyceryl trinitrate, Nitroglycerin, Nitroglycerin (product), Nitroglycerin (substance), NITROGLYCERIN PREPARATION, nitroglycerine, Nitroglycerol, Trinitrate Glyceryl, Brand name/Anginine (Nitroglycerin), Brand name/Deponit patch (Nitroglycerin), Brand name/Minitran (Nitroglycerin) patches, Brand name/Nitro-bid (Nitroglycerin), Brand name/Nitro-bid ointment (Nitroglycerin), Brand name/Nitrodisc patch (Nitroglycerin), Brand name/Nitro-Dur patch (Nitroglycerin), Brand name/Nitrogard (Nitroglycerin), Brand name/Nitroglyn SA (Nitroglycerin), Brand name/Nitrolingual spray (Nitroglycerin), Brand name/Nitrong SR (Nitroglycerin), Brand name/NitroQuick (Nitroglycerin), Brand name/Nitrostat (Nitroglycerin), Brand name/Transderm-Nitro patch (Nitroglycerin), Brand name/Trinipatch (Nitroglycerin), Synonym/Glyceryl trinitrate (Nitroglycerin) admin

Treatment

Drug Dosage

DRUG/Dose 0.3 mgm (Unit/Pill/Capsule size)

DRUG/Dose 0.4 mgm (Unit/Pill/Capsule size)

DRUG/Dose 0.6 mgm (Unit/Pill/Capsule size)

DRUG/Dose Extended time release/XT/SA (example)

DRUG/Dose Infusion mix 50 mgm/250 ml (CONFIRM this)

DRUG/Dose iv 10-40 microgrms/min

DRUG/Dose PRN (as needed)

DRUG/Generic available

DRUG/Infusion option medication

DRUG/Inhaled/aerosolized medication (example)

DRUG/Injectable medication (parenteral)

DRUG/Sub-lingual preparation/administration

Definition

Vasodilating nitrate drug; NO direct vasodilator to coronary (and other) arteries;lingual or oral or parenteral preparation;tachyphylaxis occurs

(Edit)

External Links Related to Nitroglycerin (Nitrostat) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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