Disease Information for Nitrogen mustard (HN2/Mustargen) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Hair loss
Non-scarring Alopecia/balding
Disease Progression
Pancytopenia with Hypocellular Marrow
Laboratory Tests
Abnormal Lab Findings - Decreased
Lymphocytes (Lab)
Neutrophiles (Lab)
Abnormal Lab Findings - Increased
Uric acid, serum (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Anemia
Bone marrow failure/exhaustion
Drug induced Anemia.
Drug induced Baldness/Alopecia
Drug induced Neutropenia.
Drug induced Thrombocytopenia.
Granulocytopenia/Neutropenia
Hyperuricemia
Myelosuppression
Disease Mechanism & Classification
Drugs
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Nitrogen mustard alkylating agent
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Treatment
Drug Dosage
DRUG/.1990 or before
Definition

Antineoplastic cancer chemotherapy drug. Alkylating agents

are radiomimetic and interfere with methylation of DNA during cell devision. Nitrogen mustards are some of the first developed in this group.

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External Links Related to Nitrogen mustard (HN2/Mustargen) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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