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- Disease Information
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Major Organs-Systems ▼
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Disease Information for Neuroblastoma, CNS
- Clinical Manifestations
- Signs & Symptoms
- High blood pressure child
- High blood pressure/sign
- Ataxia
- Nystagmus
- Staggering Gait
- Constitutional symptoms
- Opsoclonus/chaotic eye movements
- True Vertigo Sign Confirmed
- Clinical Presentation & Variations
- Presentation/Ataxia in a Child Acute
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- Chromosomal abnormality (Lab)
- Abnormal Lab Findings - Increased
- Catecholamines serum (Lab)
- Dopamine (Lab)
- Norepinephrine, plasma (Lab)
- Vanillyl-Mandelic Acid/VMA (Lab)
- URINE Arylsulfatase
- URINE Catecholamines
- URINE Homovanillic acid
- URINE Metanephrines
- URINE VMA
- Diagnostic Test Results
- Isotope Scan
- Isotope/MIBG I131 scan abnormal (metaiodobenzylguanidine)
- CT Scan
- MRI/Head Scan Abnormal
- Associated Diseases & Rule outs
- Rule Outs
- Meningioma
- Associated Disease & Complications
- Encephalopathy, myoclonic infantile (Kinsbourne)
- Encephalopathy, myoclonic, infantile
- Hypertension in a child
- Intracranial Mass/Effect
- Myoclonic encephalopathy/childhood
- Neuroblastoma/CNS
- Ataxia Disorder
- Intracranial Lesion
- Mass in Brain
- Disease Mechanism & Classification
- Class
- CLASS/Brain/CNS disorder (ex)
- CLASS/Neurologic (category)
- Pathophysiology
- Pathophysiology/Neural crest cells/APUD tumors (ex)
- Pathophysiology/Oncogene WT1/locus 11p
- Pathophysiology/Radioresistant malignancy/relative
- Pathophysiology/CNS mass lesion effect
- Process
- PROCESS/Malignancy in childhood (ex)
- PROCESS/Malignancy/cancer (ex)
- PROCESS/Neoplastic (category)
- PROCESS/Congenital neoplasm (ex)
- Treatment
- Drug Therapy - Indication
- RX/Chemotherapy combination/protocol
- RX/Chemotherapy(cancer)
- Definition
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Neuroblastomas are neural tumors and abnormalities that have cell origins from the neural crest; ICD-9CM CODES; 194_0 Neuroblastoma, unspecified site; 8% of all solid tumors of childhood; Male >female ratio Childhood; Infants and children; N-myc protooncogene; loss of short arm chromosome 1 (1p36) found in some children; CLINICAL: Mass in abdomen, neck, or chest; Spinal cord compression; Dancing eyes; Chronic pain; Ecchymosis around eyes; Weight loss; Fever; DIFFERENTIAL: Other childhood tumors; Wilms’ tumor; Diagnosis: Biopsy of tumor; Urinary catecholamines; Bone marrow aspiration; CT scan or MRI abdomen/chest or head; there is hope for recovery with aggressive treatment ;Surgery; Multiagent chemotherapy (eg, cyclophosphamide, vincristine, dacarbazine, melphalan, doxorubicin, cisplatin); Radiotherapy ;either death or cure ;Overall survival is >40% Survival in stage I is >95%, whereas survival in stage II is <20% [Evans classification];-------[Ferri"s Clinical advisor 2005]--------
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- External Links Related to Neuroblastoma, CNS
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)