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Disease Information for Nesiritide (Natrecor) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Dizzy on Standing/Giddy Response

Low Blood Pressure

Orthostatic drop in blood pressure

Laboratory Tests

Abnormal Lab Findings - Increased

Brain Natiuretic Peptide/BNP level (Lab)

NT-proBNP indicator levels (N-terminal)

Associated Diseases & Rule outs

Associated Disease & Complications

Drug induced Hypotension Hypovolemia

Drug induced Renal failure,

Hypotension

Hypovolemia

Orthostatic hypotension syndrome

Disease Mechanism & Classification

Drugs

DRUG/ Source rDNA Manufacture

DRUG/Diuretic medication (example)

DRUG/Genetically engineered/biological drug (example)

DRUG/Lowers pulmonary wedge pressure/CHF

DRUG/Specialized usage (example)

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

Nesiritide (Natrecor) Administration, Brand name/Natrecor (Human Naturetic Peptide), Brand name/Natrecor (Nesiritide/hBNP), Synonym/B type Natriuretic peptide/human admin, Synonym/hBNP admin/infusion, Synonym/Naturetic peptide (hBNP) admin, Synonym/Neseritide (human B-type Naturetic peptide) adm

Treatment

Drug Dosage

DRUG/.$$$$$ Most Expensive

DRUG/2002 new drug (RX)

DRUG/Dose Bolus method/infusion rate (CONFIRM this)

DRUG/Dose special schedule/course

DRUG/Dose Unit dose Vial preparation

DRUG/Infusion option medication

DRUG/Injectable medication (parenteral)

DRUG/Injectable preparation only

DRUG/Intravenous administraton RX

DRUG/Intravenous only RX

Definition

Bioengineered drug; Brain naturetic hormone; atrium human B type naturetic peptide; intravenous bolus preparation for acute CHF; causes renal failure and very expensive; [johnson & Johnson] intravenous dosing only; good afterload reducing drug for failure;

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External Links Related to Nesiritide (Natrecor) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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