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Disease Information for Nephrogenic Systemic Fibrosis

Clinical Manifestations
Signs & Symptoms: Cutaneous manifestations; Intracutaneous edema signs; Skin thickening over fingers; Thickened skin/diffuse; Tightness of skin/sensation; Wooden Induration extremities
: Edema of Lower Extremities; Edema Upper Extremity; Edema/hands and feet; Flexion contractures/extremities; Forearms/legs involved; Muscle weakness; Stiffness; Stiffness/swelling lower extremities; Symmetrical muscle involvement/stiffness; Upper extremity swelling
: Arthralgias Polyarthralgias; Joint Pains
Clinical Presentation & Variations: Presentation/Uremic MRI then Systemic Sclerosis
Demographics & Risk Factors
Established Disease Population: Patient/Uremia/Chronic renal disease
Sex & Age Groups: Population/Adult/all
Diagnostic Test Results
Pathology: BX/Skin biopsy/Abnormal; BX/Skin Collagen Bundles Thickened; BX/Skin Collagen Clefts Mucin and Fibrocytes
: BX/Muscle Biopsy Abnormal; PATH/Distal Myonecrosis/Myositis
: PATH/Collagen swelling/tissue specimen
Isotope Scan: Isotope/Bone scan abnormality
Associated Diseases & Rule outs
Rule Outs: Scleroderma, progressive systemic
Associated Disease & Complications: Contractures/scars; Edema; Nephrogenic Systemic Fibrosis
Disease Mechanism & Classification
Class: CLASS/Dermatologic/Subcutaneous (category); CLASS/Skin disorder (ex)
: CLASS/Muscle/tendon/extremities (category)
: CLASS/Systemic/no comment (category)
Process: PROCESS/Bilateral occurrence; PROCESS/Collagen disease (ex); PROCESS/Drug induced disorder (ex); PROCESS/Iatrogenic (category); PROCESS/INCIDENCE/Extremely rare disease
: PROCESS/Systemic illness (ex)
Treatment
Other Treatments: PX/Three Successive Dialysis Cycles
Definition: Be the first to add a definition for Nephrogenic Systemic Fibrosis
External Links Related to Nephrogenic Systemic Fibrosis: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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