Differential Diagnosis
Diseases
Drugs
More
[+] Tips
- Try building your search one term at a time, and be as specific as you can! Search term example: "chronic cough".
- Do not enter multiple findings such as "anemia, chronic cough, weight loss, vomiting" all at the same time.
- After selecting your term from the search results a list of possible diagnoses will be generated. If the list is too long, you will be able to narrow it down by entering additional terms.
- Do not enter values such as "heart rhythm 110" or "sodium 125", instead use "tachycardia" or "hyponatremia".

Disease Information for Neostigmine (Prostigmin) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Slow pulse/Bradycardia

Diaphoresis profuse/active sweating/acute

Excess Sweating Children

Hyperhidrosis/Chronic sweating excess

Sweating Excess Perspiration

Active Bowel Sounds

Borborygmi/Bowel sound increased

Cholinergic symptoms/signs

Lacrimation/excess tearing

Tearing

Typical Clinical Presentation

Coma with cholinergic ( SLUD) signs

Laboratory Tests

Abnormal Lab Findings - Increased

Acetyl choline level (Lab)

Diagnostic Test Results

EKG (ECG)

EKG/Widened QRS pattern (ECG)

EKG/AV Nodal Block/Complete

EKG/Changes/abnormalities (ECG)

Associated Diseases & Rule outs

Associated Disease & Complications

Bradyarrhythmias

Cardiac conduction defects

Cholinergic crisis/toxidrome

Heart block, complete

Disease Mechanism & Classification

Drugs

DRUG/Acetylcholinesterase inhibitor

DRUG/Anti-Myasthenia Gravis medication (ex)

DRUG/Cholinergic agonist drug/effect (example)

DRUG/Enteric/gut motor stimulation

DRUG/Important Acute care drugs (example)

DRUG/Intensivist (ICU care)

DRUG/Parasympatheticomemitic effect (ex)

DRUG/Lowers seizure threshold

Pathophysiology

Pathophysiology/Acetyl choline accumulation

Pathophysiology/Peristalsis increased

Pathophysiology/Neuromuscular irritability

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Toxin

TOXIN/Decreases Heart Rate

TOXIN/SLUD response(sial/lacr/urine/dia)

Synonyms

Synonym

Benzenaminium 3 (((dimethylamino)carbonyl)oxy) N N N trimethyl, NEOSTIGMINE, Neostigmine (neuromusc transm), Neostigmine (neuromuscular transmission), Neostigmine (neuromuscular transmission) (product), Neostigmine (neuromuscular transmission) (substance), Neostigmine (product), Neostigmine (substance), NEOSTIGMINE PREPARATION, Proserine, Prozerin, Synstigmin, Brand name/Prostigmin (Neostigmine)

Treatment

Drug Dosage

DRUG/.$$$ Expensive medication

DRUG/Dose 15 mgm (Unit/Pill/Capsule size)

DRUG/Injectable medication (parenteral)

DRUG/Injectable preparation only

DRUG/Intramuscular injection RX

DRUG/Subcutaneous administration medication

Definition

Anticholinesterase inhibitor drug used in acute myasthenia gravis; ACH Inhibitors can induce cholinergic crisis syndrome; This is an injectable drug; Used also in

certain poisonings

(Edit)

External Links Related to Neostigmine (Prostigmin) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

Ads

This site is designed primarily as a reminder system for use by qualified physicians and other medical professionals. By using this site you understand and accept that DiagnosisPro.com shall not be used as a diagnostic decision-making system and must not be used to make a clinical diagnosis or replace or overrule a licensed health care professional's judgment or clinical diagnosis (full terms of use). This site complies with the HONcode standard for trustworthy health information: verify here.