Disease Information for Nefazodone (Serzone) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Hepatic toxicity
Toxic hepatitis
Disease Mechanism & Classification
Drugs
DRUG/Antidepressant medication (examples)
DRUG/Cytochrome CY P450 3A4 degradation pathway
DRUG/Serotonin reuptake inhibitor/CNS effect
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Nefazodone (Serzone) admin, Brand name/Serzone (Nefazodone)
Treatment
Drug Dosage
DRUG/.$$$ Expensive medication
DRUG/Dose 100 mgm (Unit/Pill/Capsule size)
DRUG/Dose 150 mgms (Unit/Pill/Capsule size)
DRUG/Dose 200 mgms (Unit/Pill/Capsule size)
DRUG/Dose 50 mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Drug discontinued/TOXIC (RX)
DRUG/Oral medication (ex)
Definition

An antidepressant drug; tricyclic antidepressant (TCA); all TCA medications have anti-cholinergic effects; this drug is used for depression and insomnia; oral preparation; causes drowsiness; withdrawn by manufacturer because of toxic hepatitis and liver failure side effect 2004

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External Links Related to Nefazodone (Serzone) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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