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Disease Information for Necrotizing angiitis, cutaneous

Clinical Manifestations

Signs & Symptoms

Osler's nodules/finger-tips/Osler's nodes

Cutaneous ulcer/Skin ulcer

Cutaneous ulcers/necrotic purulent base/center

Purpura, palpable

Acutely ill patient/signs

Constitutional symptoms

Disease Progression

Course/Acute

Course/Acute on subacute

Course/Chronic disorder

Onset/Acute/Course chronic

Laboratory Tests

Abnormal Lab Findings - Increased

Anti-neutrophilic/cytoplasm antibody (ANCA) (Lab)

IGG/Immunoglobulin G (Lab)

Diagnostic Test Results

Pathology

PATH/Granulomatous vasculitis

PATH/Vasculitis lesions

BX/Skin biopsy/Leukoclastic vasculitis

PATH/Granulomatous tissue/specimen

PATH/Histopathology/vasculitic

Associated Diseases & Rule outs

Associated Disease & Complications

Granulomatous Vasculitis

Nephrosis/secondary disease

Raynaud's syndrome

Vasculitis syndrome

Hypersensitivity/Leukoclastic Vasculitis

Disease Mechanism & Classification

Class

CLASS/Cardiovascular (category)

CLASS/Vasculopathy disorder (ex).

Pathophysiology

Pathophysiology/Inflamm/Malignant/vasculitic/necrosing

Pathophysiology/Leukoclastic Vasculitis

Pathophysiology/Gangrene/skin/subcutaneous tissue

Pathophysiology/Granulomatous arteritis

Process

PROCESS/Allergy/collagen/autoimmune (category)

PROCESS/Allergy/inflammatory/granulomatous disorder (ex).

PROCESS/Degenerative/necrosis disorder (category)

PROCESS/Inflammatory/Granulomatous disease (ex)

PROCESS/Inflammatory/infection (ex)

PROCESS/Necrosis (ex)

PROCESS/Granulomatous Disease

Treatment

Drug Therapy - Indication

RX/Immune-suppression

Surgical Procedures or Treatments

SX/Biopsy

Definition

Vasculitis, Cutaneous Necrotizing

Dermal Necrotizing Angiitis

Disorder Subdivisions

General Discussion

Cutaneous Necrotizing Vasculitis is characterized by inflammation and tissue damage (necrosis) of blood vessel walls and associated skin (cutaneous) lesions. Cutaneous Necrotizing Vasculitis may be a primary disease process or occur due to or in association with a number of different underlying disorders (e.g., certain infections, certain autoimmune disorders) or other factors (e.g., allergic reaction or hypersensitivity to certain medications, toxins, or inhaled environmental irritants [NORD 2005]

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External Links Related to Necrotizing angiitis, cutaneous

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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