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- Disease Information
- Disease Comparison
-
Disease Processes ▼
- Auto Immune
- Vascular-Arteriosclerosis
- Biochemical
- Congenital-developmental
- Deficiency
- Degenrative-Necrosis
- Electromagnetic-Physics
- Eponymic
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- Trauma
- Use-age-Atrophic
- Endocrine-Vegetative
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Major Organs-Systems ▼
- Systemic
- Pediatric
- Nervous & Sensory System (Neurology)
- Cardiovascular System
- Respiratory (Pulmonary) System
- Gastro-Intestinal (Digestive) System
- Urinary System
- Dermatologic System
- Endocrine System
- Immune System
- Musculoskeletal System
- Genital Reproductive System
- Hematopoietic System (Hematology)
- Lymphatic System
- Tissue/Cells/Organelles
Disease Information for Myositis synthetase syndrome/Anti-Jo-1 syndrome
- Clinical Manifestations
- Signs & Symptoms
- Skin thickening over fingers
- Finger tightness/thickening/swelling
- Hypotonia
- Cellophane crackles/rales at bases sign
- Dyspnea
- Exertional cyanosis
- Pulmonary Crackles
- Shortness of breath/SOB
- Arthralgias Polyarthralgias
- Joint Pains
- Joint pains Arthralgias in Elderly
- Morning gel stiffness
- Shoulder arthritis signs/symptoms
- Wrist arthritis/signs
- Fever
- Fever Febrile Possible
- Flu-Like Syndrome
- High body temperature
- Clinical Presentation & Variations
- Fever and High Sed Rate
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Demographics & Risk Factors
- Established Disease Population
- Patient/Dermatomyositis
- Population Group
- Middle Age Adult
- Woman
- Event, Activity, Behavioral & Seasonal Factors
- Early Morning Events Phenomenon
- Sex & Age Groups
- Population/Adult Aged Only
- Population/Adult/all
- Population/Female
- Population/Fifties adult
- Population/Middle-aged adult
- Population/Woman patient
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- Acute inflammatory markers elevated (Lab)
- SGOT(AST)/SGPT(ALT) Less than 1.0 (Lab)
- Transaminase elevation (Lab)
- HLA DR3 (Lab)
- HLA DRW52 (Lab)
- HLA Specific association (Lab)
- Abnormal Lab Findings - Decreased
- Anti-Ku antibody (labs)
- Abnormal Lab Findings - Increased
- Anti-EJ Antibody test (labs)
- Anti-Jo1 antibody (labs)
- Anti-JO-1/RNA (histidyl enzyme) (Lab)
- Anti-Mi1 antibody (labs)
- Anti-Mi2 antibody (labs)
- Anti-OJ Antibody (labs)
- Anti-Pl12 antibody (labs)
- Anti-PL-7 antibody (labs)
- Anti-RNA antibody/Nrnp (Lab)
- Anti-SRP Antibody (labs)
- Anti-U2SNRNP
- Aldolase, serum (Lab)
- ALT (SGPT) (Alanine transferase) (Lab)
- CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
- Sed Rate/ESR/Sedimentation rate (Lab)
- Diagnostic Test Results
- Pathology
- BX/Lung Abnormal (Biopsy)
- Electrodiagnosis
- EMG/Abnormal findings
- Pulse oximetry/low O2 saturation
- X-RAY
- Xray/Chest abnormal
- Xray/Chest/Lung fields/Abnormal
- Associated Diseases & Rule outs
- Rule Outs
- Dermatomyositis
- Myotonia atrophica
- Associated Disease & Complications
- Arthritis
- Bronchiolitis obliterans
- Bronchiolitis obliterans/organizing pneumonia/BOOP
- Dermatomyositis
- Hypoxemia
- Hypoxia, systemic
- Inflammatory myopathy
- Interstitial lung involvement/manifestation
- Knee arthritis
- Myopathy
- Polyarthritis syndrome/Multiple joints/weeks
- Polymyositis
- Raynaud's syndrome
- PolyArthritis
- Disease Mechanism & Classification
- Pathophysiology
- Pathophysiology/Anti-JO1 variant/more joint/lung involvement
- Pathophysiology/Exertional O2 desaturation
- Pathophysiology/Anti t-RNA synthetase
- Process
- PROCESS/Allergy/collagen/autoimmune (category)
- PROCESS/Collagen disease (ex)
- Synonyms
- Synonym
- Myositis synthetase syndrome Anti Jo 1 syndrome, Synonym/Dermatomyositis [T-RNA synthetase antibody]
- Treatment
- Drug Therapy - Indication
- RX/Corticosteroid (Cortisone)
- Definition
-
Newly described anti Jo-1 autoimmune disease (t-RNA synthetase or antihistidyl t-RNA synthetase); clinically subset of dermatomyositis manifest as interstitial lung disease, myositis, raynauds disease, arthritis of wrists, fingers, knees, and shoulders with fever; treatment corticosteroids
(Edit)
- External Links Related to Myositis synthetase syndrome/Anti-Jo-1 syndrome
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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