Disease Information for Multiple System Atrophy/Shy Dragers plus

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Clinical Manifestations
Signs & Symptoms
Akinetic rigid frozen Posture
Bowel/Stool Incontinence
Constipation in Elderly
Muscle stiffness/rigidity
Dizziness/Dizzy
Urge incontinence
Urinary Incontinence in Elderly
Heat intolerance/Warm all the time
Associated Diseases & Rule outs
Rule Outs
Dementia, Lewy body type
Associated Disease & Complications
Anhydrosis/Absent sweating/diffuse
Autonomic neuropathy
Cerebellar ataxia
Constipation
Hypovolemia
Impotence/Erectile dysfunction disorder
Olivopontocerebellar degeneration
Orthostatic hypotension syndrome
Parkinsons disease
Striatonigral degeneration
Akinetic Rigid Syndrome
Intracranial Lesion
Synonyms
Synonym
Atrophies Multisystem, Atrophies Multisystemic, Atrophy Multiple System, Atrophy Multisystem, Atrophy Multisystemic, MSA Multiple system atrophy, Multiple System Atrophies, Multiple system atrophy, Multiple system atrophy (disorder), Multiple System Atrophy Syndrome, Multisystem Atrophies, Multisystem Atrophy, Multisystemic Atrophies, Multisystemic Atrophy, Synonym/Multiple System Atrophy
Definition

Multiple System Atrophy; MSA; Progressive Autonomic Failure with Multiple System Atrophy; Shy-Drager Syndrome; (SDS); Sporadic OPCA; Sporadic Olivopontocerebellar Atrophy; Striatonigral Degeneration (SND); Multiple system atrophy (MSA) is a rare progressive neurological disorder characterized by a varying combination of symptoms; Affected individuals may experience symptoms similar to those found in Parkinson’s disease (parkinsonism); cerebellar signs such as progressive impairment of the ability to coordinate voluntary movements (cerebellar ataxia); and impaired functioning of the portion of the nervous system (autonomic nervous system) that regulates certain involuntary body functions (autonomic failure) such as heart rate, blood pressure, sweating, and bowel and bladder control; The exact cause of multiple system atrophy is unknown; The term multiple system atrophy has generated significant controversy and confusion in the medical literature; The term now encompasses three conditions once thought to be separate disorders, specifically Shy-Drager syndrome, striatonigral degeneration, and sporadic olivopontocerebellar atrophy; Additionally, there is a hereditary form of olivopontocerebellar atrophy that is not part of the multiple system atrophy spectrum; [NORD]

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External Links Related to Multiple System Atrophy/Shy Dragers plus
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Wikipedia
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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