Disease Information for MPTP/Meperidine designer drug/synthetic

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Clinical Manifestations
Signs & Symptoms
Akinetic rigid frozen Posture
Muscle spasticity
Muscle stiffness/rigidity
Stiffness
Symmetrical muscle involvement/stiffness
Akinesia/poor voluntary movement
Athetosis
Basal ganglion signs
Bradykinesia
Chorea signs
Choreoathetoid movement
Choreoathetosis
Cogwheel resistance/passive stretch
Coordination/signs
Delirium
Delirium/Agitated delirium
Extrapyramidal signs
Festinating gait
Freezing gait/sign
Gait disturbance/abnormality
Gait/no arm swing
Gait/turning en mass phenomenon
Hand tremors
Micrographia
Pill-rolling tremor/Parkinsonoid
Shuffling 'magnetic' gait
Tremor
Painful heroin injection/addict history
Diagnostic Test Results
CT Scan
CT Scan/Head lesion basal ganglia
MRI/Head lesions basal ganglia
MRI/Head Scan Abnormal
Associated Diseases & Rule outs
Rule Outs
Parkinsons disease
Tardive dyskinesia syndrome
Associated Disease & Complications
Amphetamine/speed toxidrome
Basal gangion lesion/secondary
Drug Induced Choreoathetosis
Extrapyramidal disease/manifestation
MPTP/Mepereidine designer drug toxicity
Parkinsonism, secondary
Parkinsons disease
Akinetic Rigid Syndrome
Disease Mechanism & Classification
Class
CLASS/Basal ganglia lesion/involvement/disorders (ex)
Drugs
DRUG/Addiction/hallucinagen/street drug (category)
DRUG/Black market/illegal source drug (ex)
Pathophysiology
Pathophysiology/Microhemorrhage brain foci
Toxin
TOXIN/Causes Hyperthermia/Fever
Synonyms
Synonym
MPTP Meperidine designer drug synthetic, Synonym/1-Methyl-4phenyl-1,3,5,6tetrahydropyridine, Synonym/Methylphenyltetrahdropyridine/MPTP street drug
Definition

Street drug; Derivative of meperidine (Demerol) designer drug; cause severe basal ganglion disease with wooden posture parkinsons like syndrome; oral intake; little used

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External Links Related to MPTP/Meperidine designer drug/synthetic
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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