Disease Information for Morphea

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Hair loss
Thickened skin/diffuse
White skin discoloration
Associated Diseases & Rule outs
Rule Outs
Eosinophilic fasciitis
Associated Disease & Complications
Morphea
Disease Mechanism & Classification
Class
CLASS/Dermatologic/Subcutaneous (category)
Process
PROCESS/Allergy/collagen/autoimmune (category)
PROCESS/Reference organ/system (category)
Synonyms
Synonym
MORPHEA, Morphea (disorder), Morphoea, Synonym/Scleroderma variant
Definition

A chronic, localized hardening and thickening of the skin. Lesions may be categorized as morphea (guttate, profunda, pansclerotic) or linear (with or without melorheostosis or hemiatrophy). It is twice as common in women as in men. The condition is characterized by skin ischemia, lymphocytic infiltrates, swollen collagen bundles, and thickening of the dermis with reduction of subcutaneous fat.

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External Links Related to Morphea
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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