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Disease Information for Morphea
- Clinical Manifestations
- Signs & Symptoms
- Baldness/Alopecia
- Hair loss
- Thickened skin/diffuse
- White skin discoloration
- Associated Diseases & Rule outs
- Rule Outs
- Eosinophilic fasciitis
- Associated Disease & Complications
- Morphea
- Disease Mechanism & Classification
- Class
- CLASS/Dermatologic/Subcutaneous (category)
- Process
- PROCESS/Allergy/collagen/autoimmune (category)
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- Synonyms
- Synonym
- MORPHEA, Morphea (disorder), Morphoea, Synonym/Scleroderma variant
- Definition
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A chronic, localized hardening and thickening of the skin. Lesions may be categorized as morphea (guttate, profunda, pansclerotic) or linear (with or without melorheostosis or hemiatrophy). It is twice as common in women as in men. The condition is characterized by skin ischemia, lymphocytic infiltrates, swollen collagen bundles, and thickening of the dermis with reduction of subcutaneous fat.
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- External Links Related to Morphea
- Wikipedia
- Merck
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- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)