Disease Information for Mikulicz's Syndrome

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Clinical Manifestations
Signs & Symptoms
Carious teeth/sign
Parotid swelling
Salivary Gland Enlargement
Fever
Lacrimal gland enlarged
Disease Progression
Course/Chronic disorder
Course/Chronic only
Diagnostic Test Results
Pathology
BX/Parotid gland abnormal
BX/Parotid Lymphocytic Infiltration
Associated Diseases & Rule outs
Associated Disease & Complications
Dacryoadenitis, acute
Deafness
Dental caries
Stenson's duct/blockage
Uveoparotid fever/sarcoidosis
Disease Mechanism & Classification
Class
CLASS/Jaw/dental/oral/salivary (category)
CLASS/Parotid disorder (ex)
Pathophysiology
Pathophysiology/Lymphocytic Dacrosialoadenopathia
Process
PROCESS/Eponymic (category)
PROCESS/Inflammatory/Granulomatous disorder (category)
Definition

A chronic, benign, and usually painless inflammatory swelling of the lacrimal and salivary glands; It is considered by some to include the glandular enlargement associated with other diseases, such as Sjogren's syndrome, sarcoidosis, lupus erythematosus, etc; Mikulicz Syndrome; Dacryosialoadenopathia; Dacryosialoadenopathy; Mikulicz Syndrome; Mikulicz-Radecki Syndrome; Mikulicz-Sjogren Syndrome; von Mikulicz Syndrome; Mikulicz syndrome is a chronic condition characterized by the abnormal enlargement of glands in the head and neck, including those near the ears (parotids) and those around the eyes (lacrimal) and mouth (salivary); The tonsils and other glands in the soft tissue of the face and neck may also be involved; Although the disorder is almost always described as benign, it always occurs in association with another underlying disorder such as tuberculosis, leukemia, syphilis, Hodgkin’s disease, lymphosarcoma, Sjogren syndrome, or lupus (SLE); People who have Mikulicz syndrome are at heightened risk for developing lymphomas; Some people with Mikulicz syndrome may experience recurring fevers; The fever may be accompanied by dry eyes, diminished tear production (lacrimation), and inflammation of various parts of the eyes (uveitis); Lacrimal gland enlargement, parotid gland enlargement, dry mouth and dry eyes are the classic signs; The exact cause of Mikulicz syndrome is not known; Some scientists believe that Mikulicz syndrome should be considered a form of Sjogren syndrome;

----------[NORD 2005]------------------------

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External Links Related to Mikulicz's Syndrome
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NEJM (The New England Journal of Medicine)
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