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- Disease Information
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Disease Processes ▼
- Auto Immune
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Major Organs-Systems ▼
- Systemic
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Disease Information for Microscopic Polyangiitis/PAN variant
- Clinical Manifestations
- Signs & Symptoms
- Cutaneous ulcer/Skin ulcer
- Local lesion/skin rash
- Rash
- Wrist drop
- Hemoptysis
- Arthralgias Polyarthralgias
- Migratory polyarthritis syndrome
- Fever
- Malaise
- Weight Loss
- Clinical Presentation & Variations
- Nephritis Syndrome Normal Complement
- Demographics & Risk Factors
- Established Disease Population
- Patient/Recent antibiotic treatment
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- URINE Sediment/Urinalysis abnormal
- Abnormal Lab Findings - Decreased
- Hemoglobin (Lab)
- Abnormal Lab Findings - Increased
- Anti-MPO titer (P-ANCA)/Myeloperoxidase antibody (Lab)
- Anti-neutrophilic/cytoplasm antibody (ANCA) (Lab)
- C-reactive protein (Lab)
- Highly sensitive CRP (LAB)
- P-ANCA antibodies (Lab)
- Sed Rate/ESR/Sedimentation rate (Lab)
- Serum Amyloid A (SSA)
- URINE Protein (Albumin)
- URINE Red blood cells
- Diagnostic Test Results
- Pathology
- PATH/ANCA Positive Vasculitis
- BX/Skin biopsy/Abnormal
- BX/Muscle Biopsy Abnormal
- BX/Nerve biopsy/abnormal
- BX/Renal Glomerular Crescent Formation
- BX/Renal Pauci-immune Glomerulonephritis
- CT Scan
- CT Scan/Chest abnormal
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Anemia
- Glomerulonephritis, acute
- Livedo reticularis
- Mononeuritis, multiplex
- Multi-radicular Polyneuropathy syndrome
- Nephrotic syndrome
- Polyarteritis nodosa
- Proteinuria
- Scleritis/Episcleritis
- Vasculitis syndrome
- Microscopic Polyangiitis/PAN variant
- PolyArthritis
- Hematuria
- Disease Mechanism & Classification
- Class
- CLASS/Arteriolar disorder (ex)
- CLASS/Artery disorder (ex)
- CLASS/Cardiovascular (category)
- CLASS/Small artery disorder
- CLASS/Vascular Small Vessel Disorder
- Pathophysiology
- Pathophysiology/Granulomatous/necrotizing angiitis
- Pathophysiology/Arteritis
- Pathophysiology/Small Vessel Vasculitis
- Process
- PROCESS/Allergy/collagen/autoimmune (category)
- PROCESS/Collagen disease (ex)
- Synonyms
- Synonym
- Synonym/Polyarteritis
- Treatment
- Drug Therapy - Indication
- RX/Azathioprine (Imuran)
- RX/Corticosteroid (Cortisone)
- RX/Cyclophosphamide (Cytoxan)
- RX/Prednisone (Deltasone)
- Other Treatments
- TX/Plasmapheresis/exchange.
- Definition
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subset of polyarteritis nodosa. non necrotizing but P-ANCA positive and diagnosed with biopsy of skin, muscle, or nerve evidence of small vessel arteritis. glomerulitis and pulmonary alveolar hemorrhage occur but antibodies to GBM negative. treatment with prednisone, cytoxan, or azathioprin is effective. plasmapheresisc for more severe cases if P-ANCA positive. Some overlap with SLE and PAN and much constitutional symptoms. Skin and eyes are involved often as well as Mononeuritis multiplex.
CRM 2008
(Edit)
- External Links Related to Microscopic Polyangiitis/PAN variant
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)