Disease Information for Methyldopa (Aldomet) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Breast Swelling Bilateral
Galactorrhea/Male
Lactorrhea in a male
Lactorrhea/Galactorrhea/Prolonged lactation
Hypotension with Relative Bradycardia
Low Blood Pressure
Impotence, relative
Fatigability
Stupor/poor reponse to stimulus
Fatigue
Fatigue Tiredness Exhaustion
Fever
Fever Febrile Possible
Flu-Like Syndrome
High body temperature
Clinical Presentation & Variations
Presentation/Pancreatitis Kids Recurrent
Disease Progression
Galactorrhea
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
Hyperprolactinemia
Indirect Coombs Test Abnormal
URINE Color Brown
Abnormal Lab Findings - Decreased
Platelet count (Lab)
URINE VMA
Abnormal Lab Findings - Increased
Anti-Histone antibody (Lab)
ANA, homogenous/serum (Lab)
ANA/Antinuclear antibody/Fluorescent ANA (Lab)
Anti-Nuclear Antibody (ANA)
Bilirubin, serum (Lab)
Direct Coombs test (Lab)
Indirect bilirubin (Lab)
LE Prep/Lupus erythematosis cell prep (Lab)
Prolactin (Lab)
Vanillyl-Mandelic Acid/VMA (Lab)
URINE 5-Hyroxyindole acetic acid
URINE Catecholamines
URINE Metanephrines
URINE VMA
Diagnostic Test Results
Pathology
BX/Liver biopsy/Granulomas in liver
Associated Diseases & Rule outs
Rule Outs
Fatty liver of pregnancy
Associated Disease & Complications
Bilirubinemia
Carotid sinus syncope/sensitivity
Chronic hepatitis/Active
Drug fever
Drug induced Anemia.
Drug Induced Fatigue
Drug induced Hemolytic anemia.
Drug induced Hepatic toxicity
Drug induced Impotence.
Drug induced Lupus Erythematosis/syndrome
Drug induced Neutropenia.
Drug induced Pancreatitis
Granulocytopenia/Neutropenia
Granulomatous liver/hepatitis syndrome
Gynecomastia
Hemolysis anemia/acute/active
Hemolytic anemia/autoimmune
Hypotension
Impotence/Erectile dysfunction disorder
Lupus erythematosis, systemic
Myocarditis, hypersensitivity/allergy
Pancreatitis, acute
Parkinsonism, secondary
Pleurisy
Porphyria, attack, acute intermittant
Retroperitoneal fibrosis
Sedation/torpor induced
Sympatholytic toxidrome/syndrome
Toxic hepatitis
Chronic Hepatitis
Disease Mechanism & Classification
Drugs
DRUG/Alpha-2 adrenergic central agonist/effect
DRUG/Antiadrenergic agent (ex)
DRUG/Antihypertensive medication (examples)
DRUG/Anti-hypertensive/injectable medication (example)
DRUG/Central alpha/sympatholytic action drug (example)
DRUG/Dopamine/depletor central/drug (example)
DRUG/Dopaminergic antagonist/peripheral (example)
DRUG/Injectable antihypertensive med (example)
DRUG/Older medication/little used
DRUG/Safe in pregnancy patient (B)
DRUG/Sympatholytic effect
DRUG-Liver metabolism/bile excretion
Pathophysiology
Pathophysiology/Hemolysis
Pathophysiology/Hemolytic process/effect
Pathophysiology/Granulomatous liver disease
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Hypotension relative bradycardia
TOXIN/Shock-hypovolemia effect.
TOXIN/Venous pooling/low wedge press (ex).
Synonyms
Synonym
3 Hydroxy alpha methyl L tyrosine, alpha Methyl L Dopa, Alpha methyldopa, Alphamethyldopa, L 2 Amino 2 methyl 3 (3 4 dihydroxyphenyl)propionic Acid, L Tyrosine 3 hydroxy alpha methyl, Levo 3 (3 4 Dihydroxyphenyl) 2 methylalanine, METHYLDOPA, Methyldopa (product), Methyldopa (substance), METHYLDOPA PREPARATION, O methyl DOPA, Brand name/Aldochlor (Methyldopa-Chlorothiazide), Brand name/Aldomet (Methyldopa), Brand name/Aldoril (Methyldopa-HCZ) combination
Treatment
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 125 mgms (Unit/Pill/Capsule size)
DRUG/Dose 250 mgm (Unit/Pill/Capsule size)
DRUG/Dose 500 mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Dose TID Medication
DRUG/Generic available
DRUG/Oral medication (ex)
Definition

an anti-hypertensive drug; Alpha-2 CNS (Central) adrenergic agonist mechanism; Oral and parenteral preparation; useful in pregnant patients along with hydralazine

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External Links Related to Methyldopa (Aldomet) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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