Disease Information for Methimazole (Tapazol) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Enlarged thyroid gland
Goiter/thyroid enlargement/mass
Thyroid Mass
Thyromegaly/Symmetric enlargement
Parotid swelling
Salivary Gland Enlargement
Diagnostic Test Results
Isotope Scan
Isotope/RAI Uptake low/thyroid scan (I 123)
Isotope/RAI uptake/quantitative high thyroid (I 123)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Drug induced Goiter/Thyromegaly
Drug induced Neutropenia.
Fetal anomaly
Granulocytopenia/Neutropenia
Hypothyroidism (myxedema)
Disease Mechanism & Classification
Drugs
DRUG/Anti-thyroid medication (example)
DRUG/Antithyroid thionamide medication
DRUG/Blocks organification of iodine/thyroid
DRUG/Breast milk secretion/Danger
DRUG/Teratogenic potential/effect (D plus )
Pathophysiology
Pathophysiology/Defective thyroid hormone biosynthesis
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1 Methyl 2 mercaptoimidazole, 2H Imidazole 2 thione 1 3 dihydro 1 methyl, Mercasolyl, Mercazolyl, Merkazolil, Methimazole, Methimazole (product), Methimazole (substance), METHIMAZOLE PREPARATION, Methylmercaptoimidazole, Methymazol, Thiamazole, Thiamazole preparation, Thimazol, Tiamazol, Brand name/Tapazole (Methimazole)
Treatment
Drug Dosage
DRUG/.$$$ Expensive medication
DRUG/.1990 or before
DRUG/Dose 10 mgm (Unit/Pill/Capsule size)
DRUG/Dose 5 mgm (Unit/Pill/Capsule size)
DRUG/Dose TID Medication
DRUG/Oral medication (ex)
Definition

Anti-thyroid drug; prevents thyroxin formation and release

from thyroid gland

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External Links Related to Methimazole (Tapazol) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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