Disease Information for Methadone (Dolophine) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Breast Swelling Bilateral
Impotence, relative
Individual Patients exquisitly sensitive
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Abnormal Lab Findings - Increased
FTI/Free Thyroxin Index (Lab)
Prolactin (Lab)
Thyroid Binding Globulin (Lab)
Thyroxin/T4 (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Impotence.
Drug induced Interstitial Lung disease.
Gynecomastia
Impotence/Erectile dysfunction disorder
Interstitial lung involvement/manifestation
Opiate/Morphine overdose toxidrome
Disease Mechanism & Classification
Drugs
DRUG/Chronic pain/Neuropathic pain adjunct medication
DRUG/Narcotic/analgesic drug (category)
DRUG/Narcotic/Opiate-opioid medication (example)
DRUG/Safe in pregnancy patient (B)
DRUG/Specialized usage (example)
DRUG/Synthetic opioid agonist (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
3 Heptanone 6 (dimethylamino) 4 4 diphenyl, methadone, Methadone (product), Methadone (substance), METHADONE PREPARATION, Brand name/Dolophine (Methadone), Brand name/Methadose (Methadone)
Treatment
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 10 mgm (Unit/Pill/Capsule size)
DRUG/Dose 40 mgm (Unit/Pill/Capsule size)
DRUG/Dose 5 mgm (Unit/Pill/Capsule size)
DRUG/Dose liquid/syrup/suspension form
DRUG/Dose Q6 hrs Medication
DRUG/Dose Q8 Hrs Medication
DRUG/Generic available
DRUG/Oral medication (ex)
Definition

Synthetic opiate narcotic analgesic; less euphoria and long acting drug; useful in chronic pain syndromes and addiction medicine;still respiratory depression especially late; oral preparation

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External Links Related to Methadone (Dolophine) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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