Disease Information for Metabolic Syndrome/Insulin Resistance /Obesity

Clinical Manifestations
Signs & Symptoms
High blood pressure/sign
Abdominal Distension
Abdominal distension/protrusion/sign
Abdominal Distention
Increased abdominal girth/Potbelly
Stroke syndrome/signs
Polycystic ovaries on exam
Central obesity/sign
Chronic Fatigue
Increase Waist/Hip Girth Ratio
Demographics & Risk Factors
Ethnic or Racial Factors
Asian population
Hispanic/Latino population
Population Group
Middle Age Adult
Population/Immigrant population
Family History
Family history/Diabetes mellitus
Family history/Obesity
Family history/Heart disease
Family history/Strokes/cerebral arteriosclerosis
Event, Activity, Behavioral & Seasonal Factors
Lifestyle/Morbid obesity
Lifestyle/Tobacco/cigarette smoking
Sex & Age Groups
Population/Fifties adult
Population/Man patient
Population/Middle-aged adult
Laboratory Tests
Abnormal Lab Findings (Non Measured)
LDLC Small Dense particles increased
Serum lipids increased (Lab)
Abnormal Lab Findings - Decreased
HDL (High density lipoprotein) (Lab)
Abnormal Lab Findings - Increased
C-reactive protein (Lab)
Fibrinogen, plasma (Lab)
Glucose, blood (Lab)
Insulin level (Lab)
Plasminogen Activator Inhibitor (LAB)
Serum Amyloid A (SSA)
Triglycerides (Lab)
Uric acid, serum (Lab)
URINE Glucose
URINE Microalbuminuria
Diagnostic Test Results
PATH/Fat Deposition Viscera
Associated Diseases & Rule outs
Rule Outs
Cushing's disease/Syndrome
Associated Disease & Complications
Acanthosis Nigricans/Insulin Resistance
Angina pectoris
Arteriosclerotic heart disease
Cerebral vascular accident
Coronary ischemia
Diabetes mellitus
Glucose intolerance
Insulin resistance
Ischemia, cardiac
Myocardial infarction, acute
Salt/sodium retention effect
Sleep apnea syndrome
Sleep apnea/obstructive type
Steatosis/Non-alcoholic steatosis hepatitis/NASH
Diabetes mellitus/non-insulin dep/type II
Disease Synergy - Causes
Risk/Sedentary Life style/No exercise
Synergy/Sedentary life style
Disease Mechanism & Classification
Pathophysiology/Proinflammatory/Inflammatory State
Pathophysiology/Neuropeptide Y and Y2 receptor
Pathophysiology/Leptin Resistance
PROCESS/Familial variant (ex)
PROCESS/Metabolic/storage disorder (category)
abdominal obesity metabolic syndrome, AOMS1, Cardiovascular Syndrome Metabolic, Cardiovascular Syndromes Metabolic, Dysmetabolic Syndrome X, Insulin Resistance Syndrome X, Metabolic Cardiovascular Syndrome, Metabolic syndrome X, Metabolic syndrome X (disorder), Metabolic X Syndrome, Reaven Syndrome X, Reaven's syndrome, Syndrome Metabolic Cardiovascular, Syndrome Metabolic X, Syndrome X Dysmetabolic, Syndrome X Insulin Resistance, Syndrome X Metabolic, Syndrome X Reaven, X Syndrome Metabolic, Synonym/IRS-Insulin Resistance Syndrome, Synonym/Metabolic Syndrome X
Drug Therapy - Indication
RX/Low-dose aspirin
Other Treatments
TX/Weight loss diet

acquired disorder of western lifestyle but grand predisposition with familial traits of central obesity, hypertension, minimal exercise, alcohol intake especially beer, hyperlipidemia mostly triglycerides but chylomicrons and cholesterolemia; biggest characteristic and common pathway to progression is insulin resistance; obesity and non-exercise life style; heart attack, stroke, diabetes, occur early; often non compliant ansd sometimes difficult patients; responds to exercise even without much weight loss; Metabolic syndrome is a cluster of conditions that occur together, increasing your risk for heart disease, stroke and diabetes; Doctors have talked about this constellation of risk factors for years and have called it many names, including syndrome X and insulin resistance syndrome; Obesity, particularly around your waist (having an "apple shape")Elevated blood pressure ; An elevated level of the blood fat called triglycerides and a low level of high-density lipoprotein (HDL) cholesterol Resistance to insulin; One study showed that men with three factors of metabolic syndrome are nearly twice as likely to have a heart attack or stroke and more than three times as likely to develop heart disease as are those with no factors; ;In people with insulin resistance, cells don"t respond to insulin and glucose can"t enter the cells; This results in higher than normal levels of insulin and glucose in the blood; Increased insulin raises your triglyceride level and those of other blood fats; It also interferes with how your kidneys work, leading to increased blood pressure; These combined effects of insulin resistance put you at risk of heart disease, stroke, diabetes and other conditions; They think some people are genetically prone to insulin resistance; But being overweight and inactive are major contributors;


External Links Related to Metabolic Syndrome/Insulin Resistance /Obesity
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)