Disease Information for Mercaptopurine (Purinethol) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Hair loss
Non-scarring Alopecia/balding
Clinical Presentation & Variations
Presentation/Pancreatitis Kids Recurrent
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Macrocytosis/smear (Lab)
Abnormal Lab Findings - Decreased
Niacin/Nicotinic Acid serum (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Drug induced Baldness/Alopecia
Drug induced Pancreatitis
Fanconi acquired renal syndrome
Fetal anomaly
Pancreatitis, acute
Pellagra/Niacin deficiency
Disease Mechanism & Classification
Drugs
DRUG/Anti-tumor antimetabolite (example)
DRUG/Breast milk secretion/Danger
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Prevents transplant/allograft rejection
DRUG/Purine antagonists (example)
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1 7 Dihydro 6H purine 6 thione, 1 7 Dihydro 6H purine 6 thione Monohydrate, 3H Purine 6 thiol, 6 Mercaptopurine, 6 MP, 6 Purinethiol, 6 Thiohypoxanthine, 6 Thiopurine, 6 Thioxopurine, 6H Purine 6 thione 1 7 dihydro, 6H Purine 6 thione 1 7 dihydro (9CI), 6MP, 6MP Mercaptopurine, 7 Mercapto 1 3 4 6 tetrazaindene, Mercapto 6 purine, mercaptopurine, Mercaptopurine (product), Mercaptopurine (substance), MERCAPTOPURINE A 06, MERCAPTOPURINE PREPARATION, Mercapurin, Mern, MP, Purine 6 mercapto, Purine 6 thiol (8CI), Brand name/6-MP (Mercaptopurine), Brand name/Purinethol (Mercaptopurine)
Definition

Cancer chemotherapy drug; Antimetabolite class usually substituted purine or pyrimidine bases interfere with DNA synthesis

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External Links Related to Mercaptopurine (Purinethol) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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