Disease Information for Meningococcal meningitis
Epidemic meningitis, Meningitis meningococcal, Meningitis Meningococcic, meningococcal meningitis, Meningococcal meningitis (disorder), Neisseria meningitides meningitis
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Epidemic meningitis, Meningitis meningococcal, Meningitis Meningococcic, me... (more)
A fulminant infection of the meninges and subarachnoid fluid by the bacterium NEISSERIA MENINGITIDIS, producing diffuse inflammation and peri-meningeal venous thromboses. Clinical manifestations include FEVER, nuchal rigidity, SEIZURES, severe HEADACHE, petechial rash, stupor, focal neurologic deficits, HYDROCEPHALUS, and COMA. The organism is usually transmitted via nasopharyngeal secretions and is a leading cause of meningitis in children and young adults. Neisseria meningitidis serogroups A, B, and C have been reported to cause meningitis. (From Adams et al., Principles of Neurology, 6th ed, pp689-701; Curr Opin Pediatr 1998 Feb;10(1):13-8)
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A fulminant infection of the meninges and subarachnoid fluid by the bacteri... (more) (edit)
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Demographics & Risk Factors[next]
- Exposure Factors
- Travel, Geographic & Climate Related Factors
- Past History
- Recent Event
- Established Disease Population
- Population Group
- Population/Immigrant population
- Population/Pediatrics population
- Status/Boot-camp inductee
- Occupational Factors
- Event, Activity, Behavioral & Seasonal Factors
- Sex & Age Groups
- Population/Adult-Aged Only
- Population/Children/all
- Population/Elderly/Aged patient
- Population/Fetal-newborn
- Population/Infant
- Population/Seventies adult
- Population/Sixties-adult
- Population/Young adult
Clinical Manifestations[previous][top][next]
- Typical Clinical Presentation
- Fever in Humoral Immune Defect
- Presentation/Fever in Recent Immigrant/Home country visit
- Presentation/Fever recent Travel/long visit return
- Presentation/Fever/rash/prostration/abrupt
- Presentation/Opisthotonus/persistant/infant
- Fever in Asplenic Patient
- Disease Progression
- Course/Acute
- Course/Acute only
- Course/Fulminant/Precipitous
- Course/Lethal
- Course/Lethal possible/not usual
- Course/Potentially lethal/untreated
- Course/Prognosis bad/usually
- Course/Severe illness
- Course/Slow curve fast break/over hours
- Course/Untreated mortality high
- Lethal Potential
- Signs & Symptoms
- Aged Adult
- Child
- Infant
- Rigors/Shaking chills
- Young Adult
- Neck muscle pains
- Red/erythema skin discoloration
- Tachycardia/Fast heart rate
- Bruising/Ecchymosis
- Dependent purpura/sign
- Diaphoresis profuse/active sweating/acute
- Erythematous generalized rash
- Fever and Rash
- Fingernails brittle/thinner/splitting
- Hemorrhagic rash
- Hemorrhagic/Confluent ecchymotic rash
- Macular rash
- Papular Rash
- Petechiae/Petechial rash
- Purpura
- Rash
- Rash hand/foot areas
- Rash on palms and soles
- Rash, macular/maculopapular or morbilliform
- Sweats/excess perspiration
- Excessive/easy bruising tendency
- Nausea
- Projectile vomiting
- Vomiting
- Vomiting in infancy
- Absent focal neurologic signs/expected
- Altered mental status/Mental status change
- Bilateral abdominal reflex decreased
- Brudzinski's sign positive
- Changing neurologic signs, rapid
- CNS symptoms/signs
- Cognitive defect
- Confusion/agitation on exam
- Confusion/Disoriented
- Cranial nerve abnormalities/involvement/signs
- Delirium
- Delirium/Agitated delirium
- Difficulty flexing neck
- Dysarthria
- Facial Nerve Palsy/Facial Paralysis
- Facial weakness/droop, unilateral
- Febrile seizure/children
- Fluctuating consciousness
- Focal neurologic deficit
- Fontanelle bulging, infant
- Head retraction/infant
- Headache
- Headache, severe
- Headache, sudden severe and new type/Thunderclap
- Headache/worsened by movement
- Impaired judgement/signs
- Infant Seizures
- Irritability/short tempered
- Kernigs sign
- Neurological symptoms/signs
- Obtunded/poorly responsive status/signs
- Papilledema on exam
- Seizures
- Seizures/newborn
- Slow speech
- Stiff neck/Nuchal rigidity
- Stupor/poor reponse to stimulus
- Sudden unconsciousness
- Unconscious/Narcosis status
- Widening skull sutures/infant
- Hallucination/visual
- Acute Back Pain
- Arthritis fever and rash presentation
- Back Pain
- Backache
- Neck pain
- Red or inflammed pharynx
- Sore throat in Elderly
- Sore throat/Pharyngitis
- Sore Throat/Throat Pain
- Acute sepsis syndrome
- Acutely ill patient/signs
- Chills
- Collapse/Prostration
- Debilitated
- Fever
- Fever in elderly
- Fever in Immigrants
- Fever in kids
- Fever, high
- Fever/Febrile Possible
- Flu-Like Syndrome
- High body temperature
- Infant peevish/irritable/fretful
- Malaise
- Sudden death of an infant
- Toxic and febrile/septic
- Blurred Optic Disk Margin
- Diplopia/Double vision
- Nerve deafness, recent onset
- Photophobia/Light sensitive
- Visual symptoms
- Typical Clinical Presentation
Laboratory Tests[previous][top][next]
- Microbiology & Serology Findings
- Microlab/Nasopharyngeal culture/positive
- Microlab/Throat culture positive
- Microlab/Bacteria capsule effect
- Microlab/Cocci on smear
- Microlab/Culture requires CO2 for growth
- Microlab/Diplococci morphology
- Microlab/Direct fluorescent antibody/DFA abnormal
- Microlab/Gram negative diplococci/smear
- Microlab/Niesseria meningococcus isolation/agent
- Microlab/PCR/Antigen test/Abnormal
- Microlab/Quelling capsular swelling test/Abnormal
- Microlab/CSF Culture abnormal
- Microlab/CSF Latex antigen/abnormal
- Microlab/CSF Meningococcus antigen present
- Microlab/Gram/stain CSF abnormal
- Microlab/PCR CSF antigen/abnormal
- Abnormal Lab Findings (Non Measured)
- Abnormal Lab Findings - Decreased
- Abnormal Lab Findings - Increased
- Microbiology & Serology Findings
Diagnostic Test Results[previous][top][next]
- Other Tests & Procedures
- Pathology
- CT Scan
Associated Diseases & Rule outs[previous][top][next]
- Rule Outs
- Associated Disease & Complications
- Anemia
- Bacteremia/Septicemia
- Bells palsy/Facial nerve paralysis
- Central diabetes insipidus
- Cerebral spastic diplegia
- CNS disease/involvement
- Cognitive/learning disability
- Coma in Children
- Coma in Elderly
- Coma/Unconscious
- Convulsions (grand mal)
- Cranial nerve palsy
- Deafness
- Deafness, congenital
- Deafness, sensorineural
- Death Outcome
- Dehydration
- Encephalitis, bacterial
- Endocarditis, infective
- Endocarditis, right heart
- Facial nerve palsy/secondary
- Febrile convulsion
- Glomerulonephritis, postinfectious
- Hemiparesis
- Hemiplegia
- Hydrocephalus, acute acquired
- Hydrocephalus, chronic acquired
- Hyperglycemia
- Hyperpyrexia
- Hyponatremia
- Inappropriate ADH secretion syndrome
- Infantile muscular spasms/Hypsarrhythmia
- Leukocytosis
- Meningitis
- Meningitis, bacterial
- Meningitis, chronic
- Meningococcal arthritis
- Meningococcal meningitis
- Meningococcemia/Meningococcus
- Mental retardation
- Optic neuritis
- Organic brain syndrome
- Pharyngitis, acute septic
- Pneumonia, aspiration
- Prerenal azotemia
- Seizure disorder (epilepsy)
- Status epilepticus
- Subdural effusion
- Sudden death/Child
- Suppurative labyrinthitis
- Viral exanthematous diseases
- Waterhouse-Friderichsen syndrome
- Childhood Seizures
- Facial Paralysis
- Disease Synergy - Causes
- Synergy/Asplenic/splenectomy
Disease Mechanism & Classification[previous][top][next]
- Specific Agent
- AGENT/Airborne droplet spread usual/infection
- AGENT/Bacteria (category)
- AGENT/Encapsulated bacteria (ex).
- AGENT/Endemic disease (ex)
- AGENT/Highly Contagious/infectious
- AGENT/Non-motile bacteria (example)
- AGENT/Person to person contact/spread/hands
- AGENT/Sporadic infectious/cases reported
- Class
- CLASS/Reportable/CDC/National list infection (ex)
- CLASS/Meninges/pia/arachnoid involvement (ex)
- CLASS/Neurologic (category)
- Pathophysiology
- Pathophysiology/Cytokine gene polymorphism
- Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
- Pathophysiology/Blood-brain barrier leak
- Pathophysiology/CSF Pressure Increased
- Pathophysiology/Nasal colonization/commensural infection
- Process
- PROCESS/Acute infection (ex).
- PROCESS/Complicating disorder (ex)
- PROCESS/Complicating/Specific process disorder (ex)
- PROCESS/INCIDENCE/Regional specific
- PROCESS/Infected organ/abscess (category)
- PROCESS/Infection/agent specific (category)
- PROCESS/Inflammatory/infection (ex)
- Specific Agent
Treatment[previous][top][next]
- Drug Therapy - Indication
- RX/Antibiotic
- RX/Cefotaxime (Claforan)
- RX/Ceftriaxone (Rocephin)
- RX/Cefuroxime (Zenacef)
- RX/Parenteral antibiotics required
- RX/Penicillin
- RX/Prophylactic measures/medication
- RX/Sulfa drug
- RX/Sulfisoxazole (Gantrisin)
- RX/Vaccination/immunization prophylaxis
- RX/Vaccine available may be indicated
- Other Treatments
- TX/Immunization/prevention
- TX/Infection/isolation/quarantine
- Drug Therapy - Indication
External Links Related to Meningococcal meningitis[previous][top]
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