Disease Information for Melanoma, malignant
Malignant melanoma site stage unspecified
Melanoma, Malignant; Melanoblastoma; Melanocarcinoma; Melanoepithelioma; Melanoma; Melanosarcoma; Melanoscirrhus; Melanotic Carcinoma; Nevus Pigmentosa; Three Subdivisions: 1)Acral Lentiginous Melanoma;2) Juvenile Melanoma, Malignant;3) Malignant Lentigo (Melanoma); A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites; It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo; Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved; The incidence of malignant skin melanomas is rising rapidly in all parts of the world---------(Stedman, 25th ed; from Rook et al, Textbook of Dermatology, 4th ed, p2445)---------------
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Clinical Manifestations[next]
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Course/Prognosis bad/usually
- Signs & Symptoms
- Axilla Mass
- Facial ulceration/ulcers
- Bluish/black pigmentation/nails
- Brown skin discoloration
- Halo nevus/new/multiple
- Multiple depigmented areas/post vaccination
- Scalp nodule/white hair patch
- Subcutaneous nodules
- Oral pigmentation lesions
- Axillary adenopathy
- Epitrochlear adenopathy
- Epitrochlear adenopathy/unilateral
- Inguinal adenopathy/unilateral
- Inguinal/groin adenopathy
- Lymphadenopathy
- Lymphadenopathy, systemic
- Regional adenopathy
- Supraclavicular adenopathy
- Tender adenopathy/unilateral
- Femoral swelling/mass
- Inguinal Mass/Swelling
- Mass in Lower Extremity
- Multiple organ/system failure patient
- Disease Progression
Laboratory Tests[previous][top][next]
- Abnormal Lab Findings (Non Measured)
- Abnormal Lab Findings - Decreased
- Abnormal Lab Findings - Increased
Diagnostic Test Results[previous][top][next]
- Pathology
- X-RAY
- X-RAY With contrast
- Angiography
Associated Diseases & Rule outs[previous][top][next]
- Rule Outs
- Associated Disease & Complications
- Amelanotic melanocarcinoma
- Dermatomyositis
- Disseminated intravascular coagulation
- Glomerulonephritis, membranous
- Intestinal/bowel obstruction
- Melanoma, malignant
- Metastasis to adrenal glands
- Metastasis to esophagus
- Metastasis to heart/myocardium
- Metastasis to pericardium/myocardium
- Metastasis to spleen
- Metastasis to testis/scrotum
- Metastasis/epidural spinal cord
- Metastasis/inguinal nodes
- Metastatic bone disease
- Metastatic brain disease
- Metastatic liver disease
- Myelophthisic anemia
- Nephrosis/secondary disease
- Peritoneal metastasis
- Small bowel obstruction
- Mass in Lung
- Eyelid Cancer
Disease Mechanism & Classification[previous][top][next]
- Class
- CLASS/Dermatologic/Subcutaneous (category)
- Pathophysiology
- Pathophysiology/Blood vessel/vascular cancer spread
- Pathophysiology/Gene locus Chromosome 10
- Pathophysiology/Gene locus Chromosome 10q
- Pathophysiology/Gene locus Chromosome 11
- Pathophysiology/Gene locus Chromosome 9
- Pathophysiology/Gene Locus Identified/OMIM database
- Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
- Pathophysiology/Oncogene CDKN2 (CMM2/p16)/Locus 9p
- Pathophysiology/Oncogene INK4/Locus 9p
- Pathophysiology/Oncogene PRCA1/Locus 10q
- Pathophysiology/Radioresistant malignancy/relative
- Pathophysiology/Regional lymph node tumor spread
- Pathophysiology/Neoplastic invasion/pericardium
- Process
- PROCESS/Ethnic predilection (ex)
- PROCESS/Malignancy/cancer (ex)
- PROCESS/Neoplastic (category)
- PROCESS/Metastasis to stomach/gastrum (tendency) (ex)
- Class
-
- Synonym
- Synonym/Malignant melanoma
- Synonym
Treatment[previous][top][next]
- Drug Therapy - Contraindication
- RX/Levodopa (Dopar)
- Drug Therapy - Indication
- RX/Chemotherapy(cancer)
- RX/Dacarbazine (Carboximide)
- RX/Hydroxyurea (Hydrea)
- RX/Interferon alpha
- RX/Interleukin-2
- RX/Lymphocyte-activated killer cells (LAK)
- RX/Tumor-infiltrating lymphocytes (TIL)
- Surgical Procedures or Treatments
- SX/Biopsy
- SX/Surgery
- Other Treatments
- TX/Platelet transfusion
- Drug Therapy - Contraindication
External Links Related to Melanoma, malignant[previous][top]
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