Disease Information for Mechlorethamine (Mustargen) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Baldness/Alopecia
Hair loss
Non-scarring Alopecia/balding
Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Anemia
Anemia, aplastic
Bone marrow failure/exhaustion
Drug induced Anemia.
Drug induced Hair loss
Drug induced Myelosuppression.
Drug induced Neutropenia.
Drug induced Thrombocytopenia.
Erythema multiforme
Fetal anomaly
Granulocytopenia/Neutropenia
Mechlorethamine (Mustargen) effect/toxicity
Myelosuppression
Thrombocytopenia
Thrombocytosis
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Late leukemia/lymphoma complication
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Bis(2 chloroethyl)methylamine, Chloramin, Chlorethazine, Chlormethine, chloromethine, ethanamine 2 chloro N (2 chloroethyl) N methyl, HN 2, HN2, mechlorethamine, Mechlorethamine (product), Mechlorethamine (substance), MECHLORETHAMINE PREPARATION, methylchlorethamine, Mustard, Mustine, NH 2, NH2, Nitrogen mustard, NM, Brand name/HN2 (Mechlorethamine), Brand name/Mustargen (Mechlorethamine), Synonym/Nitrogen mustard administration
Treatment
Drug Dosage
DRUG/.1990 or before
Definition

Cancer chemotherapy drug; Nitrogen mustard; Early drug and powerful; Primarily an Anti-neoplastic cancer chemotherapy drug; all Alkylating agents interfer with methylation of DNA in mitosis, inhibits cell division; Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often; has been used in auto-immune disease; oral and parenteral preparation

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External Links Related to Mechlorethamine (Mustargen) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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