Disease Information for Malignant histiocytosis

Ads
Clinical Manifestations
Signs & Symptoms
Chest Pain
Excess Sweating Children
Fever and Rash
Hyperhidrosis/Chronic sweating excess
Purpura
Rash
Sweating Excess Perspiration
Lymphadenopathy
Lymphadenopathy Systemic
Hepatosplenomegaly
Palpable Liver/Hepatomegaly
Weak/Weak as a kitten (symptom)
Chest pain/non-cardiac
Chest Wall Pain
Acute Back Pain
Back Pain
Backache
Splenomegaly
Chronically ill patient/signs
Enervated/extreme acute fatigue
Fever
Fever Febrile Possible
Flu-Like Syndrome
High body temperature
Weakness
Weakness non-neuromuscular/systemic
Weight Loss
Clinical Presentation & Variations
Presentation/Lymphopenia Candidal diarrhea
Disease Progression
Course/Chronic only
Course/Lethal
Course/Prognosis bad/usually
Course/Relentless
Pancytopenia with Infiltrated Marrow
Demographics & Risk Factors
Family History
Family history/Blood disease
Sex & Age Groups
Population/Adult/all
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
Chronic lymphopenia
Leukopenia
Right Shift (Viral) Differential Smear (Lab)
Abnormal Lab Findings - Decreased
WBC
Hematocrit (Lab)
Hemoglobin (Lab)
Lymphocytes (Lab)
Platelet count (Lab)
RBC/Red Blood Count (Lab)
WBC/White Blood Cell Count/Leukocytes (Lab)
Abnormal Lab Findings - Increased
ACE/Angiotensin converting enzyme level (Lab)
Lymphocytes (Lab)
Diagnostic Test Results
Pathology
Bone marrow/Erythrophagocytosis
Bone marrow/Histiocyte hypertrophy/infiltrate
BX/Bone Marrow Biopsy/Abnormal
BX/Lymph node biopsy/abnormal
PATH/Histiocyte hypertrophy/infiltration tissue
PATH/Erythrophagocytosis/Spleen
PATH/Histiocyte hypertrophy/infiltrate spleen/nodes/RES
Associated Diseases & Rule outs
Rule Outs
Mastoiditis
Pancytopenia
Associated Disease & Complications
Anemia
Candida albicans infection
Lymphocytopenia
Lymphocytosis
Malignant histiocytosis
Metastatic liver disease
Thrombocytopenia
Disease Mechanism & Classification
Class
CLASS/Langerhan Cell/Tissue Macrophages involvement/disorder (ex)
CLASS/Hematologic (category)
CLASS/Leukocyte involvement/disorder (ex)
CLASS/Marrow involvement/disorder (ex)
CLASS/Epiphyses Lesion/Involvement
CLASS/Reticuloendothelial system (RES) disorder (ex)
CLASS/Spleen/thymus/RES/immune system (category)
Pathophysiology
Pathophysiology/Histiocyte/macrophage disorder (ex)
Pathophysiology/Bone marrow infiltration
Pathophysiology/Decreased T Cells
Pathophysiology/Immune/cellular system disorder (ex)
Process
PROCESS/Autosomal recessive disorder (ex)
PROCESS/Hereditary/Genetic predisposition (ex)
PROCESS/Hereditofamilial variant/pedigrees reported (ex)
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Lymphomas (ex)
PROCESS/Malignancy/cancer (ex)
PROCESS/Neoplastic (category)
PROCESS/Blood dyscrasia/leukemic process (ex)
PROCESS/Leukemia process (ex).
Synonyms
Synonym
Histiocyt medull reticulos, Histiocytic medullary reticul, Histiocytic Medullary Reticuloses, Histiocytic medullary reticulosis, Histiocytic medullary reticulosis (disorder), Histiocytic medullary reticulosis (morphologic abnormality), Histiocytic medullary reticulosis (obs), Histiocytoses Malignant, HISTIOCYTOSIS MALIGNANT, HMR, Malignant Histiocytoses, Malignant histiocytosis, Malignant histiocytosis (clinical), Malignant histiocytosis (disorder), Malignant histiocytosis (morphologic abnormality), Malignant histiocytosis RETIRED, Malignant midline reticulosis, Malignant reticuloendothelios, Malignant reticuloendotheliosis, Malignant reticulosis, Medullary Reticuloses Histiocytic, Medullary Reticulosis Histiocytic, Midline malignant reticulosis, Nasal T cell lymphoma, Polymorphic reticulosis, reticuloendotheliosis malignant, Reticuloses Histiocytic Medullary, RETICULOSIS ALEUKEMIC, RETICULOSIS HISTIOCYTIC MEDULLARY, RETICULOSIS MALIGNANT, RETICULOSIS MALIGNANT MIDLINE, reticulosis polymorphic, RETICULOSIS POLYMORPHORIC, Stewart's granuloma, Synonym/Familial hemophagic reticulosis, Synonym/Histiocytic leukemia, Synonym/Histiocytic medullary reticulosis, Synonym/Reticulosis, aleukemic, Synonym/Reticulosis, malignant
Treatment
Drug Therapy - Indication
RX/Chemotherapy(cancer)
Definition

A rare, usually rapidly progressive disorder, characterized by abrupt onset, fever, weight loss, hepato-splenomegaly, pancytopenia, and lymphadenopathy.

(Edit)

External Links Related to Malignant histiocytosis
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
Ads