Disease Information for Lymphoma, giant follicular

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Clinical Manifestations
Signs & Symptoms
Head and Neck Soft Tissue Mass
Lateral Neck Mass
Lump in Cervical Area
Neck Mass
Neck Posterior Triangle Mass
Matted/regional adenopathy/firm
Disease Progression
Course/Chronic only
Laboratory Tests
Abnormal Lab Findings - Increased
Lactic Dehydrogenase (LDH LH) (Lab)
Diagnostic Test Results
Pathology
BX/Lymph node biopsy/abnormal
Associated Diseases & Rule outs
Associated Disease & Complications
Lymphoproliferative disorder
Asthma Children
Atelectasis in Child
Disease Mechanism & Classification
Class
CLASS/Hematologic (category)
CLASS/Leukocyte involvement/disorder (ex)
CLASS/Lymphatics/lymph (category)
Pathophysiology
PROCESS/B-Cell Lymphoma
Process
PROCESS/Lymphomas (ex)
PROCESS/Malignancy/cancer (ex)
PROCESS/Neoplastic (category)
Synonyms
Synonym
(Nodular lymphoma Brill Symmers disease) or (reticulosarcoma follicular or nodular), Brill Symmers' disease, Brill Symmers, BRILL SYMMERS DIS, Brill Symmers Disease, Brill Symmers' disease, Disease Brill Symmers, Foll low grade B cell lymphom, FOLLIC LYMPHOMA, FOLLIC LYMPHOMA GIANT, Follicle Center Lymphoma, Follicular (nodular) non Hodgkin's lymphoma, follicular germinoblastoma, Follicular low grade B cell lymphoma, Follicular low grade B cell lymphoma (disorder), follicular lymphoma, Follicular lymphoma (morphologic abnormality), Follicular lymphoma (non Hodgkin's), Follicular Lymphoma Giant, Follicular Lymphomas, Follicular Lymphomas Giant, Follicular lymphosarcoma, Follicular Non Hodgkin Lymphoma, Follicular non Hodgkin's lymph, Follicular non Hodgkin's lymphoma, Follicular non Hodgkin's lymphoma (disorder), Follicular non Hodgkin's lymphoma unspecified, Germinoblastoma follicular, GIANT FOLLIC LYMPHOMA, Giant follicular lymphoma, Giant Follicular Lymphomas, Giant follicular lymphosarcoma, Lymphocytic lymphoma nodular, LYMPHOMA FOLLIC, Lymphoma Follicular, LYMPHOMA GIANT FOLLIC, Lymphoma Giant Follicular, lymphoma lymphocytic nodular, Lymphoma Nodular, lymphoma nodular lymphocytic, Lymphomas Follicular, Lymphomas Giant Follicular, Lymphomas Nodular, lymphosarcoma follicular, M lyoma centrbl centrcyt foll, Mal lym centr blas cyt foll, Malig lymphoma nodular, Malignant lymphoma centroblastic centrocytic follicular, Malignant lymphoma centroblastic centrocytic follicular (disorder), Malignant lymphoma centroblastic centrocytic follicular (morphologic abnormality), Malignant lymphoma centroblastic centrocytic follicular RETIRED, Malignant lymphoma follicle center, Malignant lymphoma follicle center follicular, Malignant lymphoma follicle centre, Malignant lymphoma follicle centre follicular, Malignant lymphoma follicular, Malignant lymphoma lymphocytic nodular, Malignant lymphoma nodular, Malignant lymphoma nodular ((Brill Symmers' disease)), Malignant lymphoma nodular (morphologic abnormality), Nodular (follicular) lymphoma, Nodular and Follicular Lymphomas, Nodular lymphocytic lymphoma, Nodular lymphoma, Nodular lymphoma (Brill Symmers disease), Nodular lymphoma (disorder), nodular lymphoma lymphocytic, Nodular lymphoma of unspecified site, Nodular lymphoma of unspecified site (disorder), Nodular lymphoma unspec site, Nodular Lymphomas, Nodular lymphosarcoma, Nodular malignant lymphoma, Reticulosarcoma follicular or nodular, Synonym/Brill-Symmers disease, Synonym/Giant cell lymphosarcoma, Synonym/Macrofollicular lymphoblastoma
Treatment
Drug Therapy - Indication
RX/Chemotherapy(cancer)
RX/Chlorambucil (Leukeran)
Surgical Procedures or Treatments
SX/Surgery
Other Treatments
TX/Radiotherapy.
Definition

Malignant lymphoma in which the lymphomatous cells are clustered into identifiable nodules within the lymph nodes. The nodules resemble to some extent the germinal centers of lymph node follicles and most likely represent neoplastic proliferation of lymph node-derived follicular center B-lymphocytes. This class of lymphoma usually occurs in older persons, is commonly multinodal, and possibly extranodal. Patients whose lymphomas present a follicular or nodular pattern generally have a more indolent course than those presenting with a diffuse pattern.

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Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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