Disease Information for Lyme neurologic disease

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Clinical Manifestations
Signs & Symptoms
Weakness, legs, bilateral
Ataxia
Difficulty concentrating/Distraction/Forgetful
Facial Nerve Palsy/Facial Paralysis
Facial weakness/droop, unilateral
Fatigability
Glove/stocking hypesthesia
Leg reflexes, bilateral decrease
Motor and sensory neuropathy/Polyneuropathy signs
Near recall/memory deficit/defect
Staggering Gait
Tremor
Tremor in Children
Vertigo
Chronic Fatigue
Constitutional symptoms
Enervated/extreme acute fatigue
Fatigue
Fatigue Tiredness Exhaustion
Fatigue Tiredness in Children
Fever
Good days/Bad days/'Blahs' feelings
High body temperature
Visual symptoms
Disease Progression
Course/Acute
Course/Relapsing
Course/Subacute
Onset/insidious
Demographics & Risk Factors
Exposure Factors
Exposure/Ixodes dammini tick/Deer tick
Exposure/Tick bite
Travel, Geographic & Climate Related Factors
Residence/travel/Connecticut
Residence/travel/Massachusetts
Residence/travel/Minnesota
Residence/travel/Rhode Island
Residence/travel/Wisconsin
Event, Activity, Behavioral & Seasonal Factors
Activity/Fishing
Activity/Gardening/in the garden situation
Activity/Hiking/mountain climbing
Activity/Wilderness/hiking,camping,travel
Event/Month/August
Event/Month/July
Event/Month/June
Event/Month/May
Event/Month/October
Event/Month/September
Event/Summertime manifestations
Laboratory Tests
Microbiology & Serology Findings
Serum specific antibodies increased
Microlab/Borrelia burgdorferii spirochete/isolation
Microlab/Lyme disease (ELISA/IFA) titer
Microlab/Lyme disease Western Blot positive
Microlab/PCR Lyme disease positive
Abnormal Lab Findings (Non Measured)
CSF Immunoelectrophoresis abnormal
Abnormal Lab Findings - Increased
CSF/Lyme Titer 2:1 over serum
CSF IGG
CSF IGG synthesis rate
CSF Immunoglobulin
CSF Oligoclonal banding immunoelectroelectrophoresis
Diagnostic Test Results
Pathology
PATH/Brain/Leptomeningeal Lesions
Associated Diseases & Rule outs
Rule Outs
Chronic fatique syndrome (adult 'mono')
Tabes dorsalis
Associated Disease & Complications
Bells palsy/Facial nerve paralysis
Brachial plexus neuropathy
Encephalitis
Encephalomyelitis, acute
Facial nerve palsy/secondary
Inflammatory Polyneuropathy Syndrome
Lyme disease neurologic involvement
Meningitis
Meningitis, chronic
Multi-radicular Polyneuropathy syndrome
Peripheral neuropathy
Polyneuritis
Progressive Bulbar palsy
Ataxia Disorder
Facial Paralysis
Polyneuropathy
Disease Mechanism & Classification
Specific Agent
AGENT/Arthropod/acarid/tick bourne infection (ex)
AGENT/Spirochete/Borrelia/Treponema (category)
AGENT/Tick-borne illness (ex)
Class
CLASS/Neurologic (category)
Process
PROCESS/Bimodal age distribution/incidence
PROCESS/Infection/agent specific (category)
Synonyms
Synonym
Bannwarth syndrome, Bannwarth syndrome (disorder), Bannworth's syndrome, Borrelia burgdorferi Neuroborreliosis, Lyme Borreliosis Nervous System, LYME DIS NERVOUS SYSTEM, Lyme Disease Nervous System, Lyme Neuroborreliosis, Nervous System Lyme Borreliosis, NERVOUS SYSTEM LYME DIS, Nervous System Lyme Disease, Neuroborrelioses Borrelia burgdorferi, Neuroborreliosis Borrelia burgdorferi, Neuroborreliosis Lyme, Neurological Lyme disease, Tick borne meningopolyneuritis, Synonym/Bannwarth's disease, Synonym/Garin-Bujadoux disease, Synonym/Tick-borne meningopolyneuritis
Treatment
Drug Therapy - Indication
RX/Antibiotic
RX/Ceftriaxone (Rocephin)
Definition

An infectious disease caused by a spirochete, BORRELIA BURGDORFERI, which is transmitted chiefly by Ixodes dammini (see IXODES) and pacificus ticks in the United States and Ixodes ricinis (see IXODES) in Europe;It is a disease with early and late cutaneous manifestations plus involvement of the nervous system, heart, eye, and joints in variable combinations;facial palsy,peripheral neuropathy and meningoencephalitis are seen in neurologic subset-----------

Lyme disease is caused by the bacterium Borrelia burgdorferi and is transmitted to humans by the bite of infected blacklegged ticks; Typical symptoms include fever, headache, fatigue, and a characteristic skin rash called erythema migrans. If left untreated, infection can spread to joints, the heart, and the nervous system. Lyme disease is diagnosed based on symptoms, physical findings (eg, rash), and the possibility of exposure to infected ticks; laboratory testing is helpful in the later stages of disease; Most cases of Lyme disease can be treated successfully with a few weeks of antibiotics; Steps to prevent Lyme disease include using insect repellent, removing ticks promptly, landscaping, and integrated pest management; The ticks that transmit Lyme disease can occasionally transmit other tick-borne diseases as well;

[cdc.gov 2005].

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External Links Related to Lyme neurologic disease
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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