Disease Information for Lower Motor Neuron Disorder

Clinical Manifestations
Signs & Symptoms
Anal sphincter/loss of tone/reflex
Tongue fasciculations
Interosseous muscle wasting/hand
Intrinsic hand muscle wasting/sign
Muscle Atrophy
Muscle fasciculations
Muscle tone/decreased
Muscle weakness
Thenar muscle wasting
Weakness, pharyngeal muscles/signs
Weakness/one arm
Absent deep tendon reflexes
Arm reflexes, unilateral decrease
Flaccid arm/shoulder paralysis
Flaccid muscle paralysis
Flaccid paralysis/legs
Hand reflexes decreased/unilateral
Hyporeflexia/DTRs decreased
Knee reflex decrease
Limb weakness/signs
Loss of pain of temperature sensation
Lower motor neuron lesion/signs
Monoplegia, leg
Segmental/areflexia upper extremity
Triceps reflex/decreased unilateral
Weak reflexes
Weakness/Diffuse motor loss
Weakness, Gradual Onset
Diagnostic Test Results
X-RAY With contrast
Barium Swallowing Cine Abnormality
Associated Diseases & Rule outs
Rule Outs
Associated Disease & Complications
Progressive Bulbar palsy
Disease Mechanism & Classification
Pathophysiology/Unilateral effects

Pathopysiology of lesion at anterior horn cells especially at pyramidal neuron ALS and Polio good examples but several others; manifestations are fasciculations,weakness severe muscle or dermatome or plexus pattern decreased muscle tonicity, flaccidity, decreased reflex, no clonus or spasticity, negative babinski sign [ALS startas with one limb]; Major Atrophy and denervation EMG/NCT studies effect



External Links Related to Lower Motor Neuron Disorder
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)