Disease Information for Lovastatin (Mevacor) Administration/Toxicity

Ads
Clinical Manifestations
Signs & Symptoms
Diarrhea
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Transaminase elevation (Lab)
Abnormal Lab Findings - Increased
Aspartamine aminotransferase (SGOT, AST) (Lab)
AST (SGOT) (aspartamine transferase) (Lab)
Coenzyme Q10 level
HDL (High density lipoprotein) (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Acute gastroenteritis
Colchicine effect/toxicity
Drug induced Diarrhea.
Drug induced Hepatic toxicity
Drug induced Myopathy.
Drug induced Polymyositis syndrome.
Drug induced Rebound effect
Drug induced Rebound MI/Unstable angina
Polymyalgia rheumatica
Polymyositis
Rhabdomyolysis
Statin Myopathy
Toxic hepatitis
Disease Mechanism & Classification
Drugs
DRUG/Anti-cholesterol medications (examples)
DRUG/Antilipid drug (example)
DRUG/HMG-CoA reductase inhibitor/cholesterol (example)
DRUG/metabolized by CYP 3A pathway
DRUG/Statin Medication (ex)
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
(2S) 2 Methylbutanoic Acid (1S 3R 7S 8S 8aR) 1 2 3 7 8 8a Hexahydro 3 7 dimethyl 8 (2 ((2R 4R) tetrahydro 4 hydroxy 6 oxo 2H pyran 2 yl)ethyl) 1 naphthalenyl Ester, 6 Methylcompactin, Butanoic acid 2 methyl 1 2 3 7 8 8a hexahydro 3 7 dimethyl 8 (2 (tetrahydro 4 hydroxy 6 oxo 2H pyran 2 yl)ethyl) 1 naphthalenyl ester (1S (1alpha(R*) 3alpha 7beta 8beta(2S* 4S*) 8abeta)), lovastatin, Lovastatin (product), Lovastatin (substance), LOVASTATIN PREPARATION, Lovastatin RETIRED, Mevinolin, Monacolin K, Brand name/Advicor (Lovastatin-Niacin), Brand name/Altocor (Lovastatin), Brand name/Altoprev (Lovastatin), Brand name/Mevacor (Lovastatin)
Treatment
Drug Therapy - Contraindication
RX/Itraconazole (Sporonox)
Drug Dosage
DRUG/Dose 20 mgm (Unit/Pill/Capsule size)
DRUG/Oral medication (ex)
Definition

Lipid lowering drug;HMG Coenzyme A reductase inhibitor or Statin drug;Oral preparation;Statin drugs have newly documented anti-diabetic, endothelial protective and anti-platelet function that are cardioprotective beyond lipid lowering effects alone in atherosclerosis and lipidemia

(Edit)

External Links Related to Lovastatin (Mevacor) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
Ads