Disease Information for Limbic encephalopathy/paraneoplastic

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Clinical Manifestations
Signs & Symptoms
Abnormal movements/involuntary
Confusion/agitation on exam
Confusion/Disoriented
Irritability/short tempered
Memory Loss in Elderly
Near recall/memory deficit/defect
Personality change
Rapidly progressive dementia
Seizures
Short term memory loss
Temporal lobe signs
Agitation
Neuropsychiatric symptoms
Opsoclonus/chaotic eye movements
Clinical Presentation & Variations
Presentation/Progressive Dementia
Disease Progression
Course/Chronic disorder
Course/Chronic only
Course/Subacute
Demographics & Risk Factors
Established Disease Population
Patient/Cancer
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Anti-Neuron [ANNA ] Paraneoplastic antigens (1,2,2a) abnormalities
Paraneoplastic Antibody Panel (Lab)
Abnormal Lab Findings - Increased
Anti-CRMP5/Neuronal Cytoplasm antibody
Anti-GAD antibodies
Anti-Glutamic Acid decarboxylase antibodies/GAD
Anti-Hu/ANNA-IIA Paraneoplastic antigen (Lab)
Anti-Ma/Neuronal antibodies (Lab)
Anti-Purkinje/APCA/Anti-yo titer (Lab)
Anti-Ri/ANNA-2 paraneoplastic antigen (Lab)
Anti-Ta/Neuronal antibodies (Lab)
CSF Anti-Hu (ANNA 2a) antibodies
Diagnostic Test Results
Pathology
PATH/Brain/multifocal lesions/cysts/grey and white matter
CT Scan
MRI/Head Bilateral temporal lobe lesions
MRI/Head Brain Abnormal
MRI/Head Brain FLAIR Image Abnormal
MRI/Head Gadolium contrast abnormal
MRI/Head Scan Abnormal
MRI/Head T2 and fluid -attenuated inversion recovery
PET Scan/Head abnormal
Associated Diseases & Rule outs
Associated Disease & Complications
Amnesia
CNS disease/involvement
Dementia
Depression
Encephalopathy/CNS effect
Limbic encephalopathy syndrome/paraneoplastic
Partial complex seizure
Seizure disorder (epilepsy)
Disease Mechanism & Classification
Class
CLASS/Neurologic (category)
Process
PROCESS/Autoimmune disorder (ex)
PROCESS/Degenerative/necrosis disorder (category)
PROCESS/Neoplastic (category)
PROCESS/Paraneoplastic disorder (ex)
PROCESS/Paraneoplastic neurologic disorder
PROCESS/Use/Age/atrophic disorder (category)
Treatment
Drug Therapy - Indication
RX/Gamma globulin (intravenous, high dose)
RX/High dose Steroid trial [six weeks]
RX/Immune-suppression
RX/Immunoglobulin infusion
Other Treatments
TX/Plasmapheresis/exchange.
Definition
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External Links Related to Limbic encephalopathy/paraneoplastic
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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