Disease Information for Lidocaine (Xylocaine) injection/Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Dizzy on Standing/Giddy Response
Orthostatic drop in blood pressure
Slow pulse/Bradycardia
Seizures
Psychotic behavior/symptomatic
Queer bizarre behavior/change
Laboratory Tests
Abnormal Lab Findings - Increased
URINE Methemoglobin
Diagnostic Test Results
EKG (ECG)
EKG/Prolonged QRS interval (ECG)
EKG/Widened QRS pattern (ECG)
EKG/AV Nodal Block/Complete
EKG/Sinus bradycardia (ECG)
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Rule Outs
Anxiety disorder/panic attacks
Associated Disease & Complications
Bradyarrhythmias
Cardiac conduction defects
Convulsions (grand mal)
Heart block, complete
Methemoglobinemia
Orthostatic syncope Hypotension
Paranoia reaction
Psychosis
Sinus bradycardia
Disease Mechanism & Classification
Drugs
DRUG/Anesthesiology usage
DRUG/Anti-arrhythmic medication (example)
DRUG/Cardiology usage
DRUG/Cardiovascular meds (examples)
DRUG/Class I antiarrhythmic drug (example)
DRUG/Class IB antiarrhythmic agent (example)
DRUG/Class one/sodium channel myocardial blocker (example)
DRUG/Important Acute care drugs (example)
DRUG/Local anesthetic agent (ex)
DRUG/Safe in pregnancy patient (B)
DRUG/Sodium-channel block effect/toxicity
DRUG-Liver metabolism/bile excretion
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
2 (Diethylamino) 2' 6' acetoxylidide, 2 (Diethylamino) N (2 6 dimethylphenyl)acetamide, 2 2EtN 2MePhAcN, 2 Diethylamino 2' 6' acetoxylidide, Acetamide 2 (diethylamino) N (2 6 dimethylphenyl), lidocaine, Lidocaine (Obsolete), Lidocaine (product), Lidocaine (substance), LIDOCAINE PREPARATION, Lignocaine, Omega diethylamino 2 6 dimethylacetanilide, Brand name/Emla (Prilocaine-Lidocaine) ointment, Brand name/Synera (Lidocaine) patch, Brand name/Xylocaine (Lidocaine), Brand name/Xylocard (Lidocaine), Britain-BNF/Lignocaine (Lidocaine)
Treatment
Drug Dosage
DRUG/.1990 or before
DRUG/Dose Infusion mix 2 mgm/500 ml (CONFIRM this)
DRUG/Half-life relatively short
DRUG/Infusion option medication
Definition

Anti-arrhythmia drug; local anesthetic drug; also class 1B

sodium channel myocardial blocker;accumulation usual with intravenous usage; used less often as infusion now; very popular still as short acting "caine" drug instead of procaine

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External Links Related to Lidocaine (Xylocaine) injection/Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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