Disease Information for Leuprolide (Lupron) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Hot Flushes
Impotence, relative
Amenorrhea
Amenorrhea, secondary
Hot flashes
Laboratory Tests
Abnormal Lab Findings - Decreased
FSH/Follicle Stmulating Hormone/ICSH (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Impotence.
Eunuchism
Impotence/Erectile dysfunction disorder
Osteoporosis/osteopenia
Testicular atrophy
Metabolic Bone Disease
Disease Mechanism & Classification
Drugs
DRUG/Anti-androgen effect
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Gonadotropin-releasing agonist drug (example)
DRUG/Hormonal agent/derivative medication (example)
DRUG/Hormonal agents/cancer chemotherapy (example)
DRUG/LHRH inhibitor effect/analog (agonist)
DRUG/Prostate cancer use (ex)
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Pathophysiology
Pathophysiology/Hypogonadotrophic hypogonadism
Pathophysiology/Osteoporosis Secondary
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
6 D Leucine 9 (N ethyl L prolinamide) 1 9 luteinizing Hormone releasing Factor (Pig), 6 D Leucine 9 (N ethyl L prolinamide) 10 deglycinamide Luteinizing Hormone Releasing Factor (Pig), LEUP, Leuprolide, Leuprolide (Obsolete), leuprolide acetate, LEUPROLIDE PREPARATION, Leuprorelin, Leuprorelin (product), Leuprorelin (substance), Luteinizing hormone releasing factor (pig) 6 D leucine 9 (N ethyl L prolinamide) 10 deglycinamide, Brand name/Lupron (Leuprolide), Brand name/Oaklide (Leuprolide)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Injectable medication (parenteral)
DRUG/Intramuscular injection RX
DRUG/Orally ineffective drug
DRUG/Subcutaneous administration medication
Definition

GnRH analog;Functionally gonadotropin antagonist as releasing hormone receptor is exhausted ;used in cancer chemotherapy biologic activity modifier in prostate cancer;

also used in endometriosis

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External Links Related to Leuprolide (Lupron) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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