Disease Information for Leukocyte adhesion deficiency

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Clinical Manifestations
Clinical Presentation & Variations
Presentation/Lymphopenia Candidal diarrhea
Disease Progression
Course/Chronic disorder
Course/Chronic only
Course/Prognosis bad/usually
Demographics & Risk Factors
Population Group
Child
Population/Pediatrics population
Sex & Age Groups
Population/Child
Population/Child-Infant Only
Population/Children/all
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Chromosomal abnormality (Lab)
Chronic lymphopenia
Abnormal Lab Findings - Decreased
Lymphocytes (Lab)
Abnormal Lab Findings - Increased
Lymphocytes (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Candida albicans infection
Cellular immunity defect/deficiency
Immunodeficiency
Infections
Leukocyte adhesion deficiency disease
Lymphocytopenia
Lymphocytosis
Disease Mechanism & Classification
Class
CLASS/Humoral Immune System Disorder (ex)
CLASS/Leukocyte involvement/disorder (ex)
CLASS/Spleen/thymus/RES/immune system (category)
Pathophysiology
Pathophysiology/Gene locus chromosome 21
Pathophysiology/Gene Locus Identified/OMIM database
Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
Pathophysiology/Decreased T Cells
Pathophysiology/Immune/cellular system disorder (ex)
Process
PROCESS/Congenital/developmental (category)
PROCESS/Immunodeficiency disorder/Primary
Treatment
Drug Therapy - Indication
SX/Stem cell transplant/allogenic
SX/Stem-cell transplant
Definition

Also MAC-1/LFA-1/CR3 Deficiency; An autosomal recessive disorder of WBC function characterized by recurrent or progessive necrotic soft tissue infection, periodontitis, poor wound healing, leukocytosis, and delayed (>3wk) umbilical cord detachment [merck manual 17th ed]

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External Links Related to Leukocyte adhesion deficiency
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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