Disease Information for Leptospirosis/severe (Weils) type
Disease Weil, Disease Weil's, epidemic jaundice leptospiral, FIEDLER DISEASE, Haemorrhagic leptospiral jaundice, Haemorrhagic leptospirosis with jaundice, Haemorrhagic spirochaetal jaundice, Hemorrhagic leptospiral jaundice, Hemorrhagic leptospiral or spirochetal jaundice, Hemorrhagic leptospirosis with jaundice, Hemorrhagic spirochaetal jaundice, Icteric leptospirosis, Icterohemorrhagic Leptospirosis, icterohemorrhagica leptospirosis, Infection due to Leptospira icterohemorrhagiae, Infection due to Leptospira interrogans, jaundice epidemic leptospiral, jaundice leptospiral, Jaundice Spirochetal, LANCEREAUX MATHIEU WEIL SPIROCHETOSIS, leptospiral epidemic jaundice, leptospiral jaundice, Leptospiral or spirochetal jaundice, Leptospirosis icterohaemorrh, Leptospirosis icterohaemorrhagica, LEPTOSPIROSIS ICTEROHEMORRHAGIC, Leptospirosis icterohemorrhagica, Leptospirosis icterohemorrhagica (disorder), Spirochaetal jaundice, Spirochaetosis icterohemorrhagica, spirochetal epidemic jaundice, Spirochetal jaundice, Weil, WEIL DIS, Weil Disease, WEILS DIS, Weils Disease, Weil's disease, Weil's disease (disorder)
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Disease Weil, Disease Weil's, epidemic jaundice leptospiral, FIEDLER DISEAS... (more)
Leptospirosis is a worldwide infectious disease affecting both animals and humans; Weil"s disease is the worst variant with hematuria, hemorrhagic rash, jaundice, renal failure and confusion with a dramatic relapsing prolonged course;this can be lethal; Leptospira pomona is well known as a pathogen of a mild form of leptospirosis (maladie des jeune porchers)--------------------------
Weil Syndrome; Fiedler Disease; Icteric Leptospirosis;
Icterohemorrhagic Leptospirosis; Infectious Jaundice;
Lancereaux-Mathieu-Weil Spirochetosis; Leptospiral Jaundice; Spirochetal Jaundice; Weil Disease;
Weil syndrome, a rare infectious disorder, is a severe form of the bacterial infection caused by Leptospira bacteria known as leptospirosis; Weil syndrome is characterized by dysfunction of the kidneys and liver, abnormal enlargement of the liver (hepatomegaly), persistent yellowing of the skin, mucous membranes, and whites of the eyes (jaundice), and/or alterations in consciousness; In most cases, Weil syndrome occurs among individuals who are exposed to affected animals----------[NORD 2005]---------------------------
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Leptospirosis is a worldwide infectious disease affecting both animals and ... (more) (edit)
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Demographics & Risk Factors[next]
- Exposure Factors
- Travel, Geographic & Climate Related Factors
- Recent Event
- Established Disease Population
- Population Group
- Population/Immigrant population
- Occupational Factors
- Event, Activity, Behavioral & Seasonal Factors
- Sex & Age Groups
- Population/Male
- Population/Man patient
Clinical Manifestations[previous][top][next]
- Typical Clinical Presentation
- Presentation/Charcot's triad (Rigor/jaundice/RUQ pain)
- Presentation/Fever in Recent Immigrant/Home country visit
- Presentation/Fever recent Travel/long visit return
- Presentation/fever/jaundice/renal failure/adult male
- Presentation/Fever/rash/prostration/abrupt
- Presentation/Hemorrhagic jaundice fever confusion
- Presentation/Liver/Renal/Hemolytic/febrile male
- Presentation/Painless/jaundice
- Disease Progression
- Course/2 to 3 months
- Course/Acute
- Course/Acute only
- Course/Acute stuttering course/remission/relapse 10 days
- Course/Biphasic pattern/untreated
- Course/Four to six week illness
- Course/Lethal
- Course/Lethal possible/not usual
- Course/Potentially lethal/untreated
- Course/Several months
- Course/Severe illness
- Course/Slow curve/Fast break over days
- Course/Subacute
- Incubation/10-12 days
- Incubation/5-15 days
- Incubation/Intermediate
- Lethal Potential
- Onset/Abrupt/Sudden
- Signs & Symptoms
- Man
- Rigors/Shaking chills
- Relative bradycardia/fever (Fagets sign)
- Bruising/Ecchymosis
- Fever and Rash
- Petechiae/Petechial rash
- Purpura
- Rash
- Yellow skin discoloration
- Excessive/easy bruising tendency
- Abdominal Pain
- Coffee ground vomitus
- Glove stool exam guaiac positive
- Nausea
- Steady abdominal pain
- Vomiting
- Lymphadenopathy, systemic
- Choluria/Biluria/Bilirubin urine
- Clinical jaundice/Yellow skin and eyes
- Fever with Jaundice
- Hepatomegaly
- Palpable Liver
- Tender liver/liver pain
- Yellow eyeballs/Scleral icterus
- Muscle Pain
- Myalgias
- Tender or painful muscles/Myalgias
- Altered mental status/Mental status change
- Confusion/agitation on exam
- Confusion/Disoriented
- Headache
- Headache in children
- Sudden unconsciousness
- Hemoptysis
- Arthralgias
- Joint Pains
- Joint pains/Arthralgias in Elderly
- Epistaxis, severe/persistant
- Sore throat in Elderly
- Sore throat/Pharyngitis
- Sore Throat/Throat Pain
- Coca-Cola dark (coffee colored) urine
- Dark urine
- Hematuria
- Acute sepsis syndrome
- Acutely ill patient/signs
- Chills
- Debilitated
- Enervated/extreme acute fatigue
- Fever
- Fever in Immigrants
- Fever in kids
- Fever of unknown origin/chronic fever
- Fever Remittant/Recurrent
- Fever spikes/sweats,chills
- Fever with High sed Rate
- Fever, high
- Fever, intermittant/recurrent
- Fever/Febrile Possible
- Flu-Like Syndrome
- High body temperature
- Multiple organ/system failure patient
- Toxic and febrile/septic
- Bloodshot eyes/Conjunctival injection
- Ciliary injection/perilimbal (cicumcorneal)
- Red Eyes Bilateral
- Retro-Orbital Pain
- Scleral Injection
- Typical Clinical Presentation
Laboratory Tests[previous][top][next]
- Microbiology & Serology Findings
- Serum specific antibodies increased
- Microlab/Blood culture positive
- Microlab/Enzyme linked immunosorbent assay/ELISA/abn
- Microlab/Blood culture/BACTEC 460 radiometric/abn
- Microlab/Dark field exam/blood abnormal
- Microlab/Dark field microscopic exam/abnormal
- Microlab/Difficult agent to culture
- Microlab/Fluorescent indirect antibody test/Abnormal
- Microlab/Serol/Specific titers present
- Microlab/Dark field microscopic exam/urine abnormal
- Microlab/Urine culture/pathogen present
- Stool Microscopic polys present
- Abnormal Lab Findings (Non Measured)
- High WBC/Left Shift (Lab)
- Acute inflammatory markers elevated (Lab)
- Coombs negative hemolytic anemia (Lab)
- D dimer (coagulation test) abnormal (Lab)
- Dropping hematocrit/hemoglobin (Lab)
- GGT over 120/ 2 1/2 X normal elevation (Lab)
- Left shifted differential smear (Lab)
- Liver function abnormalities (Lab)
- Renal function abnormalities (Lab)
- SGOT over 120 elevation/ 2 1/2 X normal (Lab)
- SGPT over 120/2 1/2 X normal elevation (Lab)
- Transaminase elevation (Lab)
- URINE Dipstick /Blood abnormal
- URINE Dipstick/Leukocytes Positive
- URINE Pyuria
- URINE Pyuria with negative cultures
- URINE Sediment/Urinalysis abnormal
- Abnormal Lab Findings - Decreased
- Abnormal Lab Findings - Increased
- WBC
- ALT/SGPT (Alanine transferase) (Lab)
- Ammonia blood (Lab)
- Aspartamine aminotransferase (SGOT, AST) (Lab)
- AST/SGOT (aspartamine transferase) (Lab)
- Bilirubin, serum (Lab)
- BUN/Blood urea nitrogen (Lab)
- CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
- Creatinine, serum (Lab)
- Direct bilirubin (Lab)
- Fibrin Split Products/FSP/Dimers/Monomers (Lab)
- Free hemoglobin, plasma (Lab)
- Globulin, serum (Lab)
- Indirect bilirubin (Lab)
- Lactic acid/Lactate (Lab)
- LAP/Leucine Amino Peptidase (Lab)
- Neutrophiles (Lab)
- Polychrome RBCs (Lab)
- Potassium, serum (Lab)
- PT -Prothrombin time (Lab)
- Reticulocytes (Lab)
- Sed Rate/ESR/Sedimentation rate (Lab)
- WBC/White Blood Cell Count/Leukocytes (Lab)
- URINE Bilirubin
- URINE Hematuria, microscopic
- URINE Leukocytes
- URINE Protein (albumin)
- URINE Red blood cells
- CSF Lymphocytes
- CSF Protein
- STOOL Occult blood
- Microbiology & Serology Findings
Associated Diseases & Rule outs[previous][top][next]
- Rule Outs
- Associated Disease & Complications
- Abortion/miscarriage
- Acute anuria/renal failure
- Acute hepatic necrosis/yellow atrophy
- Acute renal failure
- Anemia
- Anemia, acute
- Anemia, severe
- Azotemia in Elderly
- Azotemia/Acute
- Bilirubinemia
- Cholestasis/intrahepatic biliary obstruction
- Cholestatic Jaundice Syndrome
- Conjunctivitis
- Death Outcome
- Epistaxis/nosebleed
- Erythema nodosum
- Hemolysis anemia/acute/active
- Hemolytic Anemia
- Hemorrhagic fever syndrome
- Hepatic failure
- Hepatitis, secondary
- Hepatitis, viral (non-hepatitis/secondary)
- Hepatitis,non-viral infection
- Hyperammonemia
- Hyperglobulinemia
- Hyperkalemia
- Hyperpyrexia
- Hypotension/Low blood pressure
- Iritis
- Jaundice
- Leptospiral Meningitis
- Leptospirosis/severe (Weils) type
- Meningitis
- Meningitis, bacterial
- Meningitis, chronic
- Myocarditis, lymphocytic diffuse
- Nephritis, allergic interstitial acute
- Nephritis, interstitial
- Nephritis, secondary
- Obstructive jaundice syndrome
- Optic neuritis
- Peripheral neuropathy
- Polyarthritis syndrome/Multiple joints/weeks
- Polyneuritis
- Proteinuria
- Purpura fulminans
- Renal failure, chronic
- Septic shock/pyogenic/endotoxic
- Shock
- Thrombocytopenia
- PolyArthritis
- Proteinuria in Elderly
- Pyuria
Disease Mechanism & Classification[previous][top][next]
- Specific Agent
- AGENT/Endemic disease (ex)
- AGENT/Epizootic disease (ex)
- AGENT/Highly Contagious/infectious
- AGENT/Leptospira (category)
- AGENT/Rat vector
- AGENT/Zoonosis disease (ex)
- Class
- CLASS/Liver involvement/disorder (ex)
- CLASS/Liver/gallbladder/ducts (category)
- Pathophysiology
- Pathophysiology/Capillarities/Micro hemorrhagic process
- Pathophysiology/Hematologic manifestations/involvement
- Pathophysiology/Hemolytic process/effect
- Pathophysiology/Glissons capsule stretch/acute pain
- Pathophysiology/Hepatic manifestations/involvement
- Pathophysiology/Nephritis/tubulointerstitial
- Pathophysiology/Renal manifestations/involvement
- Process
- PROCESS/Acute infection (ex).
- PROCESS/Complicating disorder (ex)
- PROCESS/Complicating/Specific process disorder (ex)
- PROCESS/INCIDENCE/Regional specific
- PROCESS/Infection/agent specific (category)
- PROCESS/Occupational illness (ex)
- Specific Agent
-
- Synonym
- Synonym/Canicola fever
- Synonym/Fiedler's disease
- Synonym/Hepatic leptospirosis
- Synonym/Infectious spirochetal jaundice
- Synonym/Lancereaux-Mathieu-Weil disease
- Synonym/Leptospirosis ictohemorrhagica
- Synonym/Spirochetal jaundice
- Synonym/Weil's disease/severe leptospirosis
- Synonym
Treatment[previous][top][next]
- Drug Therapy - Indication
- RX/Amoxicillin (Amoxil)
- RX/Antibiotic
- RX/Doxycyline (Vibramycin)
- RX/Penicillin
- RX/Tetracycline (Achromycin)
- Other Treatments
- TX/Infection/isolation/quarantine
- Drug Therapy - Indication
External Links Related to Leptospirosis/severe (Weils) type[previous][top]
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