Disease Information for Leprosy, lepromatous type

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Clinical Manifestations
Signs & Symptoms
Facial Dysfigurement
Leonine Facies/Jowles
Loss of facial wrinkles/sign
Characteristic skin nodules
Depigmented patches, skin
Hair loss
Skin Lesions Hypopigmented Anesthetic Delayed Healing
Distal Sensory Loss
Loss of pain of temperature sensation
Chronically ill patient/signs
Eyebrow Loss
Puffy/large ear lobes/sign
Thick/Fleshy Earlobes
Typical Clinical Presentation
Arthritis with Subcutaneous/Skin Nodules
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Travel, Geographic & Climate Related Factors
Residence/travel/Mexico
Ethnic or Racial Factors
Chinese population
Established Disease Population
Patient/Leprosy
Laboratory Tests
Microbiology & Serology Findings
IGM Antibody M Lepra phenolic-glycolipid antigen
Serum IGM Specific antibodies abnormally high
Serum specific antibodies increased
High Concentration Mycopbacterium Lepra in Skin
Microlab/Serol/Specific Leprosy antibodies (PGL-1)
Microlab/Acid fast bacteria/specimen
Microlab/Mycobacteria Lepra Isolation
Microlab/Serol/Specific titers present
Abnormal Lab Findings - Increased
Globulin, serum (Lab)
Diagnostic Test Results
Other Tests & Procedures
Skin test anergy
Skin Test/Lepromin antigen positive
Pathology
BX Skin/Foam Cells macrocytic vacuoles
PATH/Foam cells macrocytic vacuoles
Associated Diseases & Rule outs
Rule Outs
Vitiligo
Associated Disease & Complications
Anergic status
Hyperglobulinemia
Testicular atrophy
Disease Mechanism & Classification
Specific Agent
AGENT/Acid-fast bacteria (category)
AGENT/Contact/cutaneous/portal of entry pathophysiology
AGENT/Endemic disease (ex)
AGENT/Incubation years later
AGENT/Mycobacterium (ex)
AGENT/Non-motile bacteria (example)
AGENT/Tropical infections/diseases
Pathophysiology/Defective Cell immunity specific
Pathophysiology
Pathophysiology/Granulomatous Infection
Pathophysiology/Axon degeneration nerve endings
Process
PROCESS/INCIDENCE/Regional specific
Synonyms
Synonym
Full lepromatous leprosy, HANSEN DISEASE MALIGNANT FORM, Lepromatous Leprosies, Lepromatous Leprosy, Lepromatous leprosy (disorder), Lepromatous leprosy (type l), Leprosies Lepromatous, Leprosy Lepromatous, leprosy LL, LL Full lepromatous leprosy, LL leprosy, Type L leprosy, Type LL leprosy, Synonym/Pretty leprosy
Treatment
Drug Therapy - Indication
RX/Antibiotic
RX/Clofazimine (Lamprene)
RX/Clofazimine Dapson Rifampicinmbintion
RX/Dapsone (Avlosulfon)
RX/Ethionamide
RX/Rifampin (Rifadin)
Other Treatments
TX/Infection/isolation/quarantine
Definition
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External Links Related to Leprosy, lepromatous type
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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