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Disease Information for Leprosy, lepromatous type

Clinical Manifestations
Signs & Symptoms: Facial Dysfigurement; Leonine Facies/Jowles; Loss of facial wrinkles/sign
: Characteristic skin nodules; Depigmented patches, skin; Hair loss; Skin Lesions Hypopigmented Anesthetic Delayed Healing
: Distal Sensory Loss; Loss of pain of temperature sensation
: Chronically ill patient/signs
: Eyebrow Loss
: Puffy/large ear lobes/sign; Thick/Fleshy Earlobes
Typical Clinical Presentation: Arthritis with Subcutaneous/Skin Nodules
Disease Progression: Course/Chronic disorder; Course/Chronic only
Demographics & Risk Factors
Travel, Geographic & Climate Related Factors: Residence/travel/Mexico
Ethnic or Racial Factors: Chinese population
Established Disease Population: Patient/Leprosy
Laboratory Tests
Microbiology & Serology Findings: IGM Antibody M Lepra phenolic-glycolipid antigen; Serum IGM Specific antibodies abnormally high; Serum specific antibodies increased
: High Concentration Mycopbacterium Lepra in Skin
: Microlab/Serol/Specific Leprosy antibodies (PGL-1)
: Microlab/Acid fast bacteria/specimen; Microlab/Mycobacteria Lepra Isolation; Microlab/Serol/Specific titers present
Abnormal Lab Findings - Increased: Globulin, serum (Lab)
Diagnostic Test Results
Other Tests & Procedures: Skin test anergy
: Skin Test/Lepromin antigen positive
Pathology: BX Skin/Foam Cells macrocytic vacuoles
: PATH/Foam cells macrocytic vacuoles
Associated Diseases & Rule outs
Rule Outs: Vitiligo
Associated Disease & Complications: Anergic status; Hyperglobulinemia; Testicular atrophy
Disease Mechanism & Classification
Specific Agent: AGENT/Acid-fast bacteria (category); AGENT/Contact/cutaneous/portal of entry pathophysiology; AGENT/Endemic disease (ex); AGENT/Incubation years later; AGENT/Mycobacterium (ex); AGENT/Non-motile bacteria (example); AGENT/Tropical infections/diseases
: Pathophysiology/Defective Cell immunity specific
Pathophysiology: Pathophysiology/Granulomatous Infection
: Pathophysiology/Axon degeneration nerve endings
Process: PROCESS/INCIDENCE/Regional specific
Synonyms
Synonym: Full lepromatous leprosy, HANSEN DISEASE MALIGNANT FORM, Lepromatous Leprosies, Lepromatous Leprosy, Lepromatous leprosy (disorder), Lepromatous leprosy (type l), Leprosies Lepromatous, Leprosy Lepromatous, leprosy LL, LL Full lepromatous leprosy, LL leprosy, Type L leprosy, Type LL leprosy, Synonym/Pretty leprosy
Treatment
Drug Therapy - Indication: RX/Antibiotic; RX/Clofazimine (Lamprene); RX/Clofazimine Dapson Rifampicinmbintion; RX/Dapsone (Avlosulfon); RX/Ethionamide; RX/Rifampin (Rifadin)
Other Treatments: TX/Infection/isolation/quarantine
Definition: Be the first to add a definition for Leprosy, lepromatous type
External Links Related to Leprosy, lepromatous type: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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