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Disease Information for Lennox-Gastaut syndrome/epilepsy
- Clinical Manifestations
- Signs & Symptoms
- Abnormal movements/involuntary
- Mental Deficiency Child
- Myoclonus/Myoclonic jerks on exam
- Seizures/Children/recurrent
- Disease Progression
- Course/Acute
- Course/Chronic disease crisis/flare/attacks
- Course/Chronic disorder
- Course/Paroxysmal
- Course/Recurrent
- Course/Recurrent illness pattern
- Course/Relapsing
- Seizures unresponsive to treatment
- Demographics & Risk Factors
- Population Group
- Child
- Population/Pediatrics population
- Sex & Age Groups
- Population/Child
- Population/Child-Infant Only
- Population/Children/all
- Diagnostic Test Results
- Electrodiagnosis
- EEG/Abnormality
- EEG/Seizure activity abnormality
- EEG/Slow Spike Wave Pattern
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Epilepsy
- Mental retardation
- Seizure disorder (epilepsy)
- Disease Mechanism & Classification
- Class
- CLASS/Pediatric disorders (ex)
- CLASS/Neurologic (category)
- Pathophysiology
- Pathophysiology/Epileptic encephalopathy
- Pathophysiology/Epileptiform/epileptic disorder
- Process
- PROCESS/Eponymic (category)
- PROCESS/Use/Age/atrophic disorder (category)
- PROCESS/Vegetative-Autonomic/Endocrine (category)
- Synonyms
- Synonym
- Gastaut syndrome, Lennox Gastaut, Lennox Gastaut syndrome, Lennox Gastaut syndrome (disorder), Lennox Gestaut syndrome, Synonym/LGS Seizure Disorder, Synonym/Spike Wave Stupor
- Treatment
- Drug Therapy - Indication
- RX/Anticonvulsants
- RX/Clobazam (Onfi)
- RX/Felbamate (Felbatol)
- RX/Rufinamide (Banzel)
- Definition
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Lennox Gastaut Syndrome; LGS; Lennox-Gastaut Syndrome (LGS) is a rare disorder that typically becomes apparent during infancy or early childhood; The disorder is characterized by frequent episodes of uncontrolled electrical disturbances in the brain (seizures) and, in many cases, abnormal delays in the acquisition of skills that require the coordination of mental and muscular activity (psychomotor retardation); Individuals with the disorder may experience several different types of seizures; Lennox-Gastaut Syndrome may be due to or occur in association with a number of different underlying disorders or conditions--- [nord 2005]--------------------------------
Lennox-Gastaut; Doose’s syndrome; Gastaut"s syndrome II;
Lennox’ encephalopathy; Lennox’ syndrome; Lennox’ variant;
Astatic petit mal syndrome; hemiconvulsion-hemiplegia-epilepsy syndrome, petit mal variant; A common epileptic syndrome which usually commences before the age of 6 with myoclonic seizures by day and tonic seizures at night, with atypical absences, head nodding, and drop attacks particularly prominent; Unconsciousness, epigastric, pharyngeal, or abdominal aura, a sensation of fear, and sucking movements are symptoms; Cerebral edema and injuries are the suspected causes; It often has a poor prognosis with progressive mental deterioration; Lennox-Gastaut seizures are so powerful and occur so frequently – as often as 200 times an hour – that mental retardation is generally unavoidable; Doose"s syndrome (when strong genetic basis) is entered as a separate entity--------------[whonamedit_com 2005]-----------------
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- External Links Related to Lennox-Gastaut syndrome/epilepsy
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)