Disease Information for Lemierre's Jugular Vein Disease

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Clinical Manifestations
Signs & Symptoms
Adolescent
Head and Neck Soft Tissue Mass
Lateral Neck Mass
Lump in Cervical Area
Neck edema
Neck Mass
Neck subcutaneous emphysema
Tachypnea/Increased respiratory rate
Neck pain
Sore throat/Pharyngitis
Sore Throat/Throat Pain
Throat Conditions
Unilateral sore throat
Constitutional symptoms
Fever
Fever, high
Disease Progression
Course/Acute
Course/Lethal
Course/Potentially lethal/untreated
Course/Severe illness
Lethal Potential
Demographics & Risk Factors
Population Group
Population/Previously well
Young Adult
Sex & Age Groups
Population/Adolescent
Population/Young adult
Laboratory Tests
Microbiology & Serology Findings
Microlab/Anaerobic culture abnormal
Abnormal Lab Findings (Non Measured)
High WBC/Left Shift (Lab)
High WBC/shift increased band forms (Lab)
Abnormal Lab Findings - Decreased
Arterial Hgb O2 saturation (Lab)
Abnormal Lab Findings - Increased
WBC
WBC/White Blood Cell Count/Leukocytes (Lab)
Diagnostic Test Results
Other Tests & Procedures
PFT/Carbon monoxide diffusion (DLCO)/Abnormal
PFT/DLCO (CO diffusion) Decreased
X-RAY
Xray/Chest abnormal
Multiple pulmonary nodules
Xray/Cavitation/Cavitary lung lesion/Chest
Xray/Infiltrate, pulmonary/Chest
Xray/Multiple infiltrates/Chest
Xray/Transient pulmonary infiltrates/Chest
Ultrasound
Ultrasound/Neck abnormal
Associated Diseases & Rule outs
Rule Outs
Infectious mononucleosis
Pneumonia, abscessing staphylococcal
Temporal/Craniotemporal arteritis
Associated Disease & Complications
Abscess, parapharyngeal
Anaerobic bacterial infection
Bacteremia Septicemia
Brain abscess
Death Outcome
Embolism, septic, cerebral
Hypoxia, systemic
Internal Jugular Vein Thrombosis Septic
Lung abscess
Neurologic side effects
Pneumonia
Pneumonia, bacterial
Pneumonia, unresolved/Chronic
Pneumonia/Bronchopneumonia
Respiratory distress (adult) syndrome
Septic pulmonary emboli
Bacteremia Anaerobic
Lemierre's Disease
Multiple Abscesses
Disease Mechanism & Classification
Specific Agent
AGENT/Anaerobes/unusual bacteria (category)
AGENT/Anaerobic bacteria (ex)
Class
CLASS/Pharyngeal involvement/disorder (ex)
CLASS/Tracheonasal/larynx/pharynx (category)
Pathophysiology
Pathophysiology/Abscess tendency
Pathophysiology/Mixed Anaerobic/Aerobic bacteria
Process
PROCESS/Acute infection (ex).
PROCESS/INCIDENCE/Rare disease (ex)
PROCESS/Infected organ/abscess (category)
PROCESS/Infection/Abscess (ex)
PROCESS/Infection/agent specific (category)
PROCESS/Thrombosing process (ex)
Treatment
Drug Therapy - Indication
RX/Antibiotic
RX/Oxygen
RX/Penicillin
Definition

Lemierre's disease or syndrome is the possible complication and terminus of severe septic sore throat with oxidative tonsillitis with necrosis and abscess pathology. Anaerobes rake over the infectious process cause seeding into internal jugular vein with thrombophlebitis and septic

emboli. These metastatic abscess occur then in the lung then spread to the brain and elsewhere. Micro emboli cause acute respiratory distress syndrome and multiple patchy pneumonia sites. Very rare often lethal . The treatment is early penicillin. Presentation is with previously

healthy teenager very sick with one week of sore throat with no improvement. Presentation includes lethargy, fever, lateral neck mass, and respiratory distress with obvious septicemia with early non diagnosed source. [Multiple Google Online sources 2008, CRM]

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External Links Related to Lemierre's Jugular Vein Disease
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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