Disease Information for Leflunomide (Arava) Administration/Toxicity

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Laboratory Tests
Abnormal Lab Findings (Non Measured)
CD4 helper T-cells decreased (Lab)
Diagnostic Test Results
Other Tests & Procedures
Skin test anergy
Associated Diseases & Rule outs
Associated Disease & Complications
Craniorachischisis/Neural tube defect
Drug induced Hepatic toxicity
Toxic hepatitis
Disease Mechanism & Classification
Drugs
DRUG/Anti-inflammatory drug (example)
DRUG/Anti-rheumatoid arthritis drug (example)
DRUG/Anti-tumor antimetabolite (example)
DRUG/Breast milk secretion/Danger
DRUG/DMARD/Disease modifying rheumatoid arthritis drug (example)
DRUG/Immune modulator drug (ex)
DRUG/Immune suppressant drug (example)
DRUG/Probably NOT safe/Pregnancy category C drug
DRUG/Prodrug Metabolism
DRUG/Pyrimidine Synthesis Inhibitor
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Leflunomide (Arava) admin, Brand name/Arava (Leflunomide), Synonym/Brother of methotrexate
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/1998 Approx. New drug (RX)
DRUG/Dose 10 mgm (Unit/Pill/Capsule size)
DRUG/Dose 20 mgm (Unit/Pill/Capsule size)
DRUG/Dose once daily (RX)
DRUG/Loading dose used medication (ex)
DRUG/Oral medication (ex)
Definition

Anti-immune drug used in rheumatoid arthritis;Cancer chemotherapy drug;Antimetabolite class usually substituted purine or pyrimidine bases interfere with DNA synthesis; its action is much like methotrexate

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External Links Related to Leflunomide (Arava) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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